All 110 actors in both American Horror Story and Grey's Anatomy
110 actors have appeared in both American Horror Story and Grey's Anatomy, across 612 episodes. The most-credited is Frances Conroy, Moira O'Hara (Old), Myrtle Snow, Shachath in American Horror Story and Eleanor in Grey's Anatomy.
| Actor | In American Horror Story | In Grey's Anatomy | Eps | Eps |
|---|---|---|---|---|
| Frances Conroy | Moira O'Hara (Old), Myrtle Snow, Shachath | Eleanor | 26 | 1 |
| Adina Porter | Beverly Hope, Lee Harris, Sally Freeman | Dr. Ramsey | 21 | 1 |
| Mare Winningham | Ms. Hazel Evers, Alicia Spencer, Rita Gayheart | Susan Grey | 14 | 6 |
| Lauren Stamile | Wife | Nurse Rose | 1 | 12 |
| Brooke Smith | Dr. Gardner | Dr. Erica Hahn | 1 | 5 |
| Debra Monk | Virginia Harding | Louise O'Malley | 4 | 7 |
| Mitch Pileggi | Art | Larry Jennings | 2 | 9 |
| Leslie Grossman | Meadow Wilton, Ashleigh, Patricia Krenwinkel | Lauren Hammer | 9 | 1 |
| John Lacy | Mikey | Zack | 2 | 1 |
| Robin Weigert | Real Mama Polk, Coucilwoman Martha Edwards, Cynthia Potter | Karen Lawrence | 5 | 1 |
| Richard T. Jones | Det. Andy Hahn | Captain Dan | 7 | 1 |
| Colby French | Officer | Mr. Filson | 4 | 1 |
| Shannon Lucio | Diana Cross | Amanda | 2 | 3 |
| Clea DuVall | Wendy Peyser | Jennifer Robinson | 5 | 2 |
| Anton Starkman | Max Ellison | Harrison Meade | 6 | 9 |
| Marla Gibbs | Cassie Royale | Joyce Ward | 1 | 4 |
| Sarah Paulson | Billie Dean Howard, Lana Winters, Susan Atkins | Young Ellis Grey | 6 | 1 |
| Thomas Barbusca | Jimmy | Link McNeil | 3 | 5 |
| Troy Winbush | Newscaster | Darren Riley | 1 | 3 |
| Camille Chen | April Mayfield | Kerry Schultz | 1 | 1 |
| Casey Thomas Brown | Hans Henkes | Keith | 3 | 1 |
| Eve Gordon | Dr. Hall | Mary Chapman | 4 | 1 |
| Gloria Laino | The Mexican, Elder #1 | Ava Gutierrez | 5 | 1 |
| Granville Ames | Detective | Eric Lincoln | 1 | 3 |
| Grey Damon | Archie Brener | Lieutenant Jack Gibson | 1 | 3 |
| Steven Culp | Brooke's Father | Dr. Parker | 1 | 4 |
| Susan Berger | Real Butcher | Lee | 4 | 1 |
| James DuMont | Foster, Dr. Morrison | Sheldon Morris | 5 | 2 |
| Celia Finkelstein | Gladys | Nurse Bridget Irving | 6 | 2 |
| Chelsea Alden | Alissa | Danielle Gordon | 3 | 1 |
| Kyle Secor | Bill | John Dickinson | 1 | 3 |
| Lisa Vidal | Stacey Ramos | Dr. Alma Ortiz | 1 | 3 |
| Elizabeth Bond | Rena | Kimmie Kepner | 1 | 2 |
| Caleb Foote | Pus Bucket | Private #1 | 3 | 1 |
| Jim Ortlieb | Ray Cunningham | Jack O'Brien | 1 | 1 |
| John Getz | Mr. St. Pierre Vanderbilt | Michael Breyers | 2 | 2 |
| Larry Cedar | Auctioneer | Dr. Cohn | 1 | 1 |
| W. Earl Brown | Phil Critter | Herb Cramer | 1 | 1 |
| William R. Moses | Frank | Steven | 1 | 1 |
| Geoffrey Rivas | Det. Jack Colquitt | Stu Vargas | 2 | 1 |
| Kasey Mahaffy | Father James | Billy Best | 2 | 1 |
| Laura Allen | Rosie | Beth Whitman | 2 | 2 |
| Brian Howe | Mark Phillips | Robert Fischer | 1 | 1 |
| Debra Christofferson | Mrs. Stone | Elaine | 1 | 1 |
| Erin Allin O'Reilly | Nurse Fuller | Jodi | 1 | 1 |
| Henry G. Sanders | Mr. Royale, Willie | Dr. Hudson | 2 | 1 |
| Jack Conley | Officer Woods | Jasper Hovey | 1 | 1 |
| John Prosky | CEO Frank | Mr. Singleton | 1 | 1 |
| Joshua Malina | Dr. David Curan | Seth Hammer | 1 | 1 |
| Kevin D'Arcy | Security Guard | Heart Patient | 2 | 1 |
| Kristin Slaysman | Missy Stone | Mrs. Arkins | 1 | 1 |
| Rodney Rowland | Milo | Brian | 1 | 1 |
| Todd Stashwick | Blake | Mr. Kramer | 1 | 1 |
| Vanessa Mizzone | Lois | Sheila Goodrich | 2 | 1 |
| Cyd Strittmatter | Nun #2, Woman in Bed | Dr. Alicia Krause | 2 | 1 |
| Ron Melendez | Mark | Will Sales | 2 | 1 |
| Chad Buchanan | Stu | Brian | 1 | 1 |
| Drew Powell | Det. Collier | Carl Shatler | 1 | 1 |
| Emil Beheshti | Surgeon #2 | Man with Plaid Bow Tie | 1 | 1 |
| Jon Bass | Milo | William Hudson | 1 | 1 |
| Kristen Ariza | Mrs. Pritchard | Angela | 1 | 1 |
| Meg Steedle | Stillborn Mother | Melissa | 1 | 1 |
| Rebecca Metz | Lorene | Brenda Lawson | 1 | 1 |
| Steven M. Gagnon | Golfing Buddy | Mr. Lepik | 1 | 1 |
| John Duerler | George | Grant | 1 | 2 |
| Betty Murphy | Sally Starns | Lulu | 1 | 1 |
| Chris McGarry | Mr. Lancaster | Danny Wayne | 1 | 1 |
| David Chisum | Jim Brown | Judge Jeffrey King | 1 | 1 |
| Eric Staves | Dustin | Luke | 1 | 1 |
| Eugene Byrd | Grayson's Partner | Danny Ford | 1 | 1 |
| Kathleen Rose Perkins | Peggy | Sarah | 1 | 1 |
| Liz Jenkins | Gloria Whitmore | Guard #3 | 1 | 1 |
| Mark Daugherty | Chan | Evan | 1 | 1 |
| Tacey Adams | Sister Colette | Widow Amos | 1 | 1 |
| Amy Farrington | Mrs. Reynolds | Mary May | 1 | 1 |
| April Grace | Nurse Naima | Greta's Sister | 1 | 1 |
| Stefanie Black | Stacey Phillips | Roxie Meyers | 1 | 1 |
| Betsy Baker | Juror #5 | Barb | 1 | 1 |
| Devon Graye | Jed Potter | Brady Hauser | 1 | 1 |
| Mark Atteberry | Doctor | Brian Williams | 1 | 1 |
| Danielle Kennedy | Tudy | Angry Woman | 1 | 2 |
| Deborah Geffner | Joanna | Mrs. Burton | 1 | 1 |
| Ron Roggé | Barker | Fire Captain | 1 | 1 |
| Bob Bancroft | Harry Kirkland | Leonard Olsen | 1 | 1 |
| David Bowe | Detective | Don | 1 | 1 |
| David Naughton | Mr. Samuels | Nick Parker | 1 | 1 |
| Gary Kraus | Mack | Louis Cardon | 1 | 1 |
| Hahn Cho | Gary Chen | Dr. Dale Wong | 1 | 1 |
| Nanrisa Lee | Marylin Chang | E.R. Nurse | 1 | 1 |
| Josh Plasse | Waiter | Chris Cleaver | 1 | 1 |
| Kirk Bovill | Phil | Brian Turner | 1 | 1 |
| Lesley Fera | Female Cooperative Agent | Ann | 1 | 1 |
| Maz Siam | Cabbie | Emir's Chief of Staff | 1 | 1 |
| Abbie Cobb | Dorothy Hudson | Francis "Frankie" Keller | 1 | 1 |
| Brett Edwards | Rattled Lieutenant | Lieutenant Matthews | 1 | 1 |
| Charlene Amoia | Woman | Dr. Kate Lachman | 1 | 1 |
| Jim Gleason | Dr. Friedman | Dr. Domner | 1 | 1 |
| John Ainsworth | EMT | Young Thatcher Grey | 1 | 1 |
| Napoleon Tavale | Juror #2 | Crew Chief | 1 | 1 |
| Yolanda Snowball | ICU Nurse | Physical Therapist | 1 | 1 |
| Clayton Farris | Assistant Director | Kevin | 1 | 1 |
| Violet Hicks | Tilly | Katie | 1 | 1 |
| Yeniffer Behrens | Volunteer | Laura Medina | 1 | 1 |
| J.T. Sherwood | Theodore | Rob Lefkowitz | 1 | 1 |
| Michael Duisenberg | Male Uniform | Policeman | 1 | 1 |
| Barbara Lee Bragg | Sheik's Mother | Betsy | 1 | 1 |
| Helen Eigenberg | Nurse | Lillian Campion | 1 | 1 |
| Preston James Hillier | SWAT Officer | Cop | 1 | 1 |
| J.B. Tadena | Ted | Nurse Adam | 1 | 1 |
| Elena Schuber | Mother | Baby's Mom | 1 | 1 |
← American Horror Story × Grey's Anatomy
Cast data from TVmaze, licensed CC BY-SA 4.0.