All 121 actors in both Brothers & Sisters and Grey's Anatomy
121 actors have appeared in both Brothers & Sisters and Grey's Anatomy, across 576 episodes. The most-credited is Marika Dominczyk, Tyler Altamirano in Brothers & Sisters and Dr. Eliza Minnick in Grey's Anatomy.
| Actor | In Brothers & Sisters | In Grey's Anatomy | Eps | Eps |
|---|---|---|---|---|
| Marika Dominczyk | Tyler Altamirano | Dr. Eliza Minnick | 9 | 11 |
| Gilles Marini | Luc Laurent | Michael | 13 | 1 |
| Mitch Pileggi | Browne Carter | Larry Jennings | 3 | 9 |
| Ryan Devlin | Seth Whitley | Bill Portman | 6 | 4 |
| Tymberlee Hill | Vanessa | Intern Claire | 3 | 16 |
| Debra Monk | Dr. Alexandra Kirby | Louise O'Malley | 1 | 7 |
| Emil Beheshti | Staffer | Man with Plaid Bow Tie | 3 | 1 |
| Marguerite Moreau | Ginny Lawford | Dr. Emma Marling | 2 | 6 |
| Kathleen M. Darcy | Loan Officer | Anesthesiologist | 1 | 10 |
| David Burke | Jack Bishop | Don | 8 | 1 |
| Shi Ne Nielson | Spa Worker | Paramedic | 1 | 7 |
| Amy Aquino | Dr. Joan Avadon | Marianne Grandy | 4 | 1 |
| Paul Cassell | Gary Morris | John Hanson | 6 | 1 |
| David Denman | Brent Lewinsky | Rick Jacobs | 1 | 1 |
| Jayne Brook | Bertha Wandell | Gwen Graber | 3 | 1 |
| Marion Ross | Ida Holden | Betty Donahue | 3 | 1 |
| Sarah Jane Morris | Julia Ridge Walker | Emily Vaughn | 1 | 1 |
| Kay Panabaker | Young Kitty Walker | Emma Anderson | 2 | 1 |
| Marty Ryan | Mike | Zach Mischer | 2 | 1 |
| Michael Hyatt | Dr. Katherine Cortez | Mariann Davidson | 2 | 1 |
| Phil Abrams | Harold Wallace | Dr. Jim Nelson | 1 | 3 |
| Max Burkholder | Jake McCallister | Duncan Pailey | 4 | 1 |
| Bill Smitrovich | Ben Ridge | Dr. Walter Carr | 1 | 2 |
| Cloie Wyatt Taylor | Vicki | Annie Cooper | 1 | 1 |
| Jim Gleason | Walter Geary | Dr. Domner | 2 | 1 |
| Josh Stamberg | Cliff | Tommy Walker | 1 | 1 |
| Marin Hinkle | Courtney McCallister | Ashley Cordova | 3 | 1 |
| Nicholas Gonzalez | Mario | Clark West | 1 | 1 |
| Rick Worthy | 2nd Lt. Collins | Ray Pelletier | 1 | 1 |
| Rose Abdoo | Miss Clara | Dr. Dawson | 1 | 1 |
| Sarah Rafferty | Gloria Pierson-Davenport | Suzanne Britland | 1 | 3 |
| Scott Haven | Umpire | Randy Begler | 1 | 1 |
| Wayne Lopez | Pedro | Paramedic #2 | 1 | 4 |
| Shelley Robertson | Lynda, Journalist | Arlene Travis | 3 | 1 |
| Romy Rosemont | The Counselor | Lea Seibert | 2 | 1 |
| Benjamin Ciaramello | Anthony Lewis | Darren Covington | 1 | 1 |
| Caroline Aaron | Elise | Connie | 1 | 1 |
| Corey Mendell Parker | Adam | Brian Wilson | 1 | 1 |
| Joan McMurtrey | Doctor Fields | Zoey Glass | 1 | 1 |
| Joe Holt | Jeffrey | Steve Beck | 1 | 1 |
| Karl T. Wright | Alan Simms | Divorce Mediator | 1 | 1 |
| Nancy Linari | Older Woman #1 | Sophie's Daughter | 1 | 1 |
| Randee Heller | Karin | Joanne | 1 | 1 |
| Sunkrish Bala | Lewis | Steve Murphy | 1 | 1 |
| Joyce Brew | Monica | Nurse | 1 | 4 |
| Maura Soden | Dr. Barbara Riley | Librarian | 2 | 1 |
| Michael Beach | Noah Guare | Mr. Baker | 2 | 1 |
| Susan Santiago | Vanessa | Blanca Rodriguez | 2 | 1 |
| Amy Motta | Lexie | Jenna Lee | 1 | 1 |
| Ann Cusack | Jamie | Amy Polus | 1 | 1 |
| Bre Blair | Ms. Nadine | Lauren Pailey | 1 | 1 |
| Cassandra Braden | Nurse | Housekeeping Staffer | 1 | 1 |
| Christopher Thornton | Aaron | Daniel Campbell | 1 | 1 |
| Crista Flanagan | Stacy Hodges | Andrea | 1 | 1 |
| Hilary Ward | Theater Patron #2 | Dr. Thompson | 1 | 1 |
| John Prosky | Ron Robinson | Mr. Singleton | 1 | 1 |
| Kathe Mazur | Ann Waterman | Mrs. Epstein | 1 | 1 |
| Michael Merton | Heckler | Dexter | 1 | 1 |
| Pamela Shaddock | Board Member | Shara Freeman | 2 | 1 |
| Pat Destro | Bonnie Hancock | Boise Nurse | 1 | 1 |
| Tyrees Allen | Dr. John Massey | Dr. Saltzman | 1 | 1 |
| Victoria Kelleher | Helen / Zoe | James's Mother | 2 | 1 |
| Kathryn Meisle | Alice Webb | Liz Monroe | 1 | 2 |
| Sarah Lilly | D.A. | Joyce Basche | 1 | 2 |
| Stephen Bishop | Rick | Firefighter | 1 | 2 |
| Aaron Krebs | Busboy | Rob Platt | 1 | 1 |
| Andrea Savo | Snack Bar Cashier | Intern #3 | 1 | 1 |
| Anita Finlay | Judge Marsha Forrest | Lady Donor | 1 | 1 |
| Burl Moseley | Campaign Manager | Jason Cooper | 1 | 1 |
| Chase Kim | Waiter | Lawyer | 1 | 1 |
| Cheryl Francis Harrington | Dr. Ruth Gibson | Adrian Nelson | 1 | 1 |
| Elaine Kagan | Judge Driscoll | Mrs. Kimberley Griswold | 1 | 1 |
| Elayn J. Taylor | Mrs. Goldberg | Loretta | 1 | 1 |
| Hugh Holub | Judge | Dr. Ben Warren | 1 | 1 |
| Jeanette Brox | Claire Feller | Shelley | 1 | 1 |
| Ned Vaughn | Michael Gradstein | Representative for the Airline | 1 | 1 |
| Ramón de Ocampo | Spencer Travis | James Benton | 1 | 1 |
| Randy Evans | Bartender | Interviewer | 1 | 1 |
| Scott Michael Campbell | Young Dennis York | Mr. Hubble | 1 | 1 |
| Sophina Brown | Bitsy Fairbank | Joyce | 1 | 1 |
| Susan Chuang | Dr. Debra Cho | Naomi Evans | 1 | 1 |
| Susan Grace | Nurse Andrea Osborn | Jane | 1 | 1 |
| Dana Lee | Simon Lao | Hospital Staff Member, Mr. Tom | 1 | 2 |
| Benjamin Patterson | Masseur | Curtis Warren | 1 | 1 |
| Brent Jennings | Officer Dunnigan | Charles Redford | 1 | 1 |
| Brock Cuchna | Waiter | Recruiting Clerk | 1 | 1 |
| Cheryl Tsai | Waitress | Security Guard | 1 | 1 |
| Délé Ogundiran | Waitress | Nurse Terri Akumbu | 1 | 1 |
| Greta Sesheta | Store Clerk | Shayna | 1 | 1 |
| Jim Turner | Interviewer | Dr. Schacter | 1 | 1 |
| John Rubinstein | Dr. Marc Wilson | Keith Kalber | 1 | 1 |
| Judith Moreland | Dr. Kate Allenby | Mrs. Baer | 1 | 1 |
| Lawrence Mandley | Sgt. Harrell | Chester Jones | 1 | 1 |
| Martha Boles | Melanie Cox | Lisa Pollock | 1 | 1 |
| Michanne Quinney | Secretary | Tori | 1 | 1 |
| Michelle Ongkingco | Dawn McCarty | Nicole Verma | 1 | 1 |
| Mitch Silpa | Quinn | Tim Ruggles | 1 | 2 |
| Sonya Leslie | Private 1st Class Mandeville | Rita | 1 | 1 |
| Tina Huang | ER Doctor | Roxanne | 1 | 1 |
| Toni Torres | Female Soldier | Annette Aranda | 1 | 1 |
| Traber Burns | Judge Arthur Gray | Andy's Lawyer | 1 | 1 |
| Amol Shah | Paramedic | Dr. Rob Stanton | 1 | 1 |
| Khamani Griffin | Alex | Wallace Anderson | 1 | 1 |
| Leonard Wu | Christopher Chao | Eddie Huang | 1 | 1 |
| Meghan Lynch | Dawn | Courtney | 1 | 1 |
| Michael Canavan | David Silver | Lawyer | 1 | 1 |
| Mickey Maxwell | Deputy | Minister | 1 | 1 |
| Rubén Garfias | Henry Martinez | Bob | 1 | 1 |
| Tess Harper | Beth Ridge | Mrs. Nelson | 1 | 1 |
| Tom Choi | Steward | Flouroscope Tech | 1 | 1 |
| Treisa Gary | Reporter #2 | Beth | 1 | 1 |
| D.W. Moffett | Michael Pellington | Allan | 1 | 1 |
| Joel Grey | Dr. Jude Bar-Shalom | Dr. Singer | 1 | 1 |
| Scott Klace | Kent Barnes | Dr. Jordan Wagner | 1 | 1 |
| Stephon Fuller | Video Editor | Gregor | 1 | 1 |
| Cantrell Harris | Michael | Rescue Worker | 1 | 1 |
| Helen Eigenberg | Mona | Lillian Campion | 1 | 1 |
| Dougald Park | Patrick | Lawyer | 1 | 1 |
| Ingrid Walters | Leah | Nurse Vivian | 1 | 1 |
| Boo Arnold | Male Hotel Guest | Mr. James | 1 | 1 |
| Michelle Noh | Michelle | Sharon Peterson | 1 | 1 |
← Brothers & Sisters × Grey's Anatomy
Cast data from TVmaze, licensed CC BY-SA 4.0.