All 161 actors in both Charmed and Grey's Anatomy
161 actors have appeared in both Charmed and Grey's Anatomy, across 645 episodes. The most-credited is Jennifer Rhodes, Penny "Grams" Halliwell in Charmed and Jean Dominy in Grey's Anatomy.
| Actor | In Charmed | In Grey's Anatomy | Eps | Eps |
|---|---|---|---|---|
| Jennifer Rhodes | Penny "Grams" Halliwell | Jean Dominy | 14 | 1 |
| Kate Anthony | Reporter Kate | Nurse Kate | 1 | 14 |
| Eric Dane | Jason Dean | Dr. Mark Sloan | 9 | 4 |
| Danielle Savre | New Phoebe | Lieutenant Maya Bishop | 1 | 7 |
| Brandon Quinn | Agent Murphy | Leo | 4 | 1 |
| Wes Ramsey | Wyatt Matthew Halliwell | Jimmy | 4 | 1 |
| Becky Wahlstrom | Lila | Lisa | 2 | 2 |
| J.D. Cullum | Demon | Lloyd, Representative | 1 | 3 |
| Melissa George | Freyja | Sadie Harris | 2 | 8 |
| Ken Marino | Miles | Brad Ackles | 2 | 1 |
| Sherri Saum | Ariel | Allison Robin Brown | 1 | 2 |
| Tim Griffin | The Rabbit | Ronny O'Malley | 1 | 5 |
| Mark Adair-Rios | Magnus | David Morris | 1 | 6 |
| Scout Taylor-Compton | Thistle | Angie | 8 | 1 |
| Anne Dudek | Denise | Elise Castor | 1 | 1 |
| Brenda Bakke | Charon | Gwen Nolan | 1 | 1 |
| Brittany Ishibashi | Receptionist | Talia | 1 | 1 |
| Clare Carey | Eva | Nikki Gibson | 1 | 1 |
| John Cho | Mark Chao | Marshall Stone | 1 | 1 |
| John Rubinstein | Dr. Berenson | Keith Kalber | 1 | 1 |
| Kerry O'Malley | Nurse Ann | Jane Collins | 1 | 1 |
| Kevin Alejandro | Malvock | Dan Pruitt | 1 | 3 |
| Bethany Joy Lenz | Lady Julia | Jenny | 1 | 2 |
| Brigid Brannagh | Tuatha | Veronica Kays | 1 | 2 |
| Dean Norris | Collector #1 | Vince | 1 | 2 |
| Pat Healy | Xavier | Tom Russell | 1 | 2 |
| Raphael Sbarge | Brent Miller | Paul | 1 | 2 |
| Susan Santiago | Lucy, Miss Henderson | Blanca Rodriguez | 2 | 1 |
| Denise Dowse | Angel of Destiny | Lorraine | 3 | 1 |
| Bernie Kopell | Coroner | Father Christopher | 1 | 1 |
| Charles Walker | Judge, Pastor | Dr. Chesney | 3 | 1 |
| Cleo King | Tanya | Robin | 1 | 3 |
| Cullen Douglas | Imp Master | Dr. Bob Richardson, Mr. Arnold | 1 | 2 |
| David Anders | Count Roget | Jim | 1 | 2 |
| Deanna Russo | Eve | Nola Marques | 1 | 2 |
| Doug Sinclair | Officer #1 | Brett Hayes | 1 | 1 |
| Geoffrey Blake | Strife | Jim | 1 | 1 |
| Kimberly Guerrero | Isabel Lightfeather | Mrs. Lindsay McNeil | 1 | 1 |
| Leslie Grossman | Phoebe's Assistant | Lauren Hammer | 1 | 1 |
| Michael Reilly Burke | Cupid | Mr. Finch | 1 | 1 |
| Patrick Fischler | Foreman | Jake Steiner | 1 | 1 |
| Rebecca McFarland | Lynn | Tara Parker | 1 | 2 |
| Rodney Rowland | Rick Gittridge | Brian | 1 | 1 |
| Sarah Rafferty | Carol | Suzanne Britland | 1 | 3 |
| Crystal Kwon | Officer Maron | Nurse Jolene | 1 | 4 |
| Alex Fernandez | Lieutenant Sanchez | FBI Agent Heyward | 1 | 2 |
| Ann Cusack | Miss Donovan | Amy Polus | 2 | 1 |
| Glenn Morshower | Agent Keyes | Walter | 2 | 1 |
| T.J. Thyne | Danny | Aaron Morris | 1 | 2 |
| Allan Louis | Dreylock | Ronald Lace | 1 | 1 |
| Andrew James Allen | Kevin | Coby McKee | 1 | 1 |
| Anthony Montgomery | Paramedic | Chris Ward | 1 | 1 |
| Audrey Wasilewski | Natalie | Nicole Waldman | 1 | 1 |
| Brooke Nevin | Hope | Tricia Hale | 1 | 1 |
| Christie Lynn Smith | Allison Michaels | Cynthia Daniels | 1 | 1 |
| David Chisum | Micah / Mitch | Judge Jeffrey King | 1 | 1 |
| Greg Cromer | Rob | Dana | 1 | 1 |
| J.P. Manoux | Stanley | Danny Nelstadt | 1 | 1 |
| John Prosky | Congressman | Mr. Singleton | 1 | 1 |
| Kathe Mazur | Prosecutor | Mrs. Epstein | 1 | 1 |
| Kathryn Joosten | Wife | Mrs. Drake | 1 | 1 |
| Kurt Fuller | John Norman | Jerry | 1 | 1 |
| Larry Cedar | Xar | Dr. Cohn | 1 | 1 |
| Lex Medlin | Inspector Smith | Byron Gibbis | 1 | 1 |
| Mandy June Turpin | Wendy | Karla | 1 | 1 |
| Markus Flanagan | Marshall | Ed Hamilton | 1 | 1 |
| Melissa Greenspan | Flo | Janet | 1 | 1 |
| Scott Allen Rinker | Sollal | Toby | 1 | 1 |
| Steven M. Porter | Health Inspector | Joey | 1 | 1 |
| Vicki Davis | Tali | Morgan Fisher | 1 | 1 |
| W. Earl Brown | Shadow | Herb Cramer | 1 | 1 |
| Wendy Benson-Landes | Joanne Hertz | Suzie | 1 | 1 |
| John Cothran, Jr. | Cecil | Ken Monroe | 1 | 2 |
| Rueben Grundy | Dr. Jessup | Jake | 1 | 2 |
| Susan Chuang | Monique | Naomi Evans | 2 | 1 |
| Bre Blair | Brenda Castillo | Lauren Pailey | 1 | 1 |
| Brian Howe | Ronny | Robert Fischer | 1 | 1 |
| Charlie Robinson | Mike | Leo Paulson | 1 | 1 |
| David Ramsey | Upper Level Demon | Jimmy Thompson | 1 | 1 |
| Ed Lauter | Sutter | Timothy Miller | 1 | 1 |
| Faran Tahir | Savard | Isaac | 1 | 1 |
| Hugh Holub | Pharmacist | Dr. Ben Warren | 1 | 1 |
| James Avery | Zola | Sam | 1 | 1 |
| James Immekus | Ryan | Andrew Langston | 1 | 2 |
| James Wellington | Craps Dealer, Croupier | Bartender | 2 | 1 |
| Kari Coleman | Interviewer | Mother | 1 | 1 |
| Larry Brandenburg | Mr. Martin | Arnie Grandy | 1 | 1 |
| Lela Lee | Tessa | Mrs. Richardson | 1 | 1 |
| Meagen Fay | Nanta | Paula | 1 | 1 |
| Michael Bunin | Security Guard | Hal | 1 | 1 |
| Molly Hagan | Karen Young | Jackie | 1 | 1 |
| Alyssa Milano | Phoebe Halliwell (Mirror World) | Haylee Peterson | 2 | 1 |
| Aaron Lustig | Dr. Harris | Judge William Benson | 1 | 1 |
| Antonio D. Charity | Minion Guard | Michael Nelson | 1 | 1 |
| Brady Smith | SWAT Commander | Mike Purdy | 1 | 1 |
| Charles Emmett | CEO | Mr. Bosson | 1 | 1 |
| Colby French | Chuck Pelham | Mr. Filson | 1 | 1 |
| F.J. Rio | Ronan | Jorge Cruz | 1 | 1 |
| Josh Daugherty | Nick | Ken Daniels | 1 | 1 |
| Kathleen Wilhoite | Nadine | Leslie Goldman | 1 | 1 |
| Kristen Ariza | Marie | Angela | 1 | 1 |
| Lou Beatty, Jr. | Clarence | Miguel Ruiz | 1 | 1 |
| Michael Mantell | Neighbor Paul | Tim Nolan | 1 | 1 |
| Michaela Watkins | Andrea | Nikki Ratlin | 1 | 1 |
| Rocky McMurray | Chauffeur | Hunter | 1 | 1 |
| Ron Melendez | Michael | Will Sales | 1 | 1 |
| Steve Monroe | The Pig | Orderly | 1 | 1 |
| Susan Balboni | Secretary | Gena | 1 | 1 |
| Keith Sellon-Wright | Minister | Surgeon #1 | 1 | 2 |
| Blake Bashoff | Duncan | Elliott Meyer | 1 | 1 |
| Dorian Gregory | Darryl Morris (Mirror World), Luther Morris | Kenneth Turner | 2 | 1 |
| Jayden Lund | Tall Man / Little John | Hulking Patient | 1 | 1 |
| Lori Alan | Cynthia | Ellen Weaver | 1 | 1 |
| Lorna Raver | Madame Theresa | Patient In ER | 1 | 1 |
| Lou Richards | Male Lawyer | Steven Basche | 1 | 1 |
| Matt Winston | Photographer | Frank Jeffries | 1 | 1 |
| Michael Patrick McGill | Ray | Bob Corson | 1 | 1 |
| Newell Alexander | Widower | Ed Beckert | 1 | 1 |
| Sally Ann Brooks | Officer at Jail | Marie Lamott | 1 | 1 |
| Scott Klace | Mr. Stewick | Dr. Jordan Wagner | 1 | 1 |
| Sean McDermott | Rod Dalvos | Jake Epstein | 1 | 1 |
| Stewart Skelton | Government Agent | Dr. Fischer | 1 | 1 |
| Tom Simmons | Coroner | Bob | 1 | 1 |
| Jordan Murphy | Patron #1 | Ray Evans | 2 | 1 |
| Sean Moran | Customs Officer, Designer | Lou Bradley | 2 | 1 |
| David Grant Wright | Suit #1 | Mr. Burton | 1 | 1 |
| Jessica Steen | Ruth Brody | Dr. Rebecca Froy | 1 | 1 |
| Lauri Johnson | Secretary | Grandma Ruth | 1 | 1 |
| Peter Breitmayer | Emcee | Carson Methodist Doctor | 1 | 1 |
| Randy Thompson | Deputy | Frank Waring | 1 | 1 |
| Richard Gilbert-Hill | Dr. Oliver Mitchell | Small Town Doc | 1 | 1 |
| Will Dixon | E.R. Doctor | Jimmy | 1 | 1 |
| Angelo Tiffe | Alan Yates | Trey Boyd | 1 | 1 |
| Catherine Kwong | Waitress | Dr. Hiatt | 1 | 1 |
| Colleen McDermott | Laura | Clara Greene | 1 | 1 |
| Heather McPhaul | O.R. Nurse | Security Officer | 1 | 1 |
| Liv Hutchings | Little Journalist | Hannah Brody | 1 | 1 |
| Matt Kaminsky | EMT | Rashy Man | 1 | 1 |
| Michael Milhoan | Arthur Casey | Doug Thomas | 1 | 1 |
| Stacy Barnhisel | Linda | Gretchen | 1 | 1 |
| Tiffany Phillips | Dorrie | Anchorwoman | 1 | 1 |
| Tracey Aileen Leigh | Leysa | Sarah Cooke | 1 | 1 |
| Alanna Boatright | Nurse | Marie | 1 | 1 |
| Brandon Molale | Rocco | Beefy Patient | 1 | 1 |
| Ewan Chung | Police Technician | Tech Guy | 1 | 1 |
| Holly Marie Combs | Piper Halliwell (Mirror World) | Heidi Peterson | 1 | 1 |
| Joe Camareno | Male Nurse | Lucas Marshall | 1 | 1 |
| Adair Tishler | Little Girl | Tori Begler | 1 | 1 |
| Danielle Bisutti | Lady of the Lake | Liz Langer | 1 | 1 |
| Johnny Sneed | Larry Henderson | Garrett | 1 | 1 |
| Larry Weissman | Patient #1 | Psych Patient #1 | 1 | 1 |
| Robert Alan Beuth | Salesman | Mr. Gordor | 1 | 1 |
| David Goryl | Ad Exec | Ron Campion | 1 | 1 |
| Ed Ackerman | Young Man | Eyeball Man | 1 | 1 |
| Obie Sims | Security Guard | Neuro Fellow | 1 | 1 |
| Alexis Raich | Little Girl | Tara Brown | 1 | 1 |
| Dona Hardy | Old Paige | Grace Bickham | 1 | 1 |
| Nichelle Hines | Nurse | Young Woman | 1 | 1 |
| Reggie Jordan | Cop | Reporter #1 | 1 | 1 |
| Mark Chadwick | Quincy | Cam Miller | 1 | 1 |
| Scott Michael Morgan | Security Tech | Patient #2 | 1 | 1 |
Cast data from TVmaze, licensed CC BY-SA 4.0.