All 135 actors in both Close to Home and Grey's Anatomy
135 actors have appeared in both Close to Home and Grey's Anatomy, across 511 episodes. The most-credited is Jeff Perry, Uncle Bill in Close to Home and Thatcher Grey in Grey's Anatomy.
| Actor | In Close to Home | In Grey's Anatomy | Eps | Eps |
|---|---|---|---|---|
| Jeff Perry | Uncle Bill | Thatcher Grey | 1 | 15 |
| Robin Pearson Rose | Doris Johnson | Patricia Murphy | 1 | 14 |
| Lauren Stamile | Karla Miller | Nurse Rose | 1 | 12 |
| Barry Shabaka Henley | Detective Lou Drummer | Mr. Patterson | 9 | 1 |
| Traber Burns | Judge Dauer | Andy's Lawyer | 9 | 1 |
| Danielle Savre | Amanda Roberts | Lieutenant Maya Bishop | 1 | 7 |
| Sumalee Montano | Melinda Mallari | Lena McCallister | 6 | 1 |
| Amanda Fuller | Sally O'Neil | Morgan Peterson | 1 | 5 |
| Freda Foh Shen | Dr. Yolanda Perrin | Missy Grant | 4 | 1 |
| Patrick Fabian | Mike Bachner | Dr. Oliver Lebackes | 2 | 2 |
| Kathleen M. Darcy | Sally Anderson | Anesthesiologist | 1 | 10 |
| Michael O'Neill | Don Wheeler | Gary Clark | 1 | 4 |
| Janora McDuffie | Greeter (Cemetery) | Janet Anderson | 1 | 6 |
| Brian Kerwin | Lee Towers | Holden McKee | 1 | 1 |
| David Denman | Tim O'Neil | Rick Jacobs | 1 | 1 |
| Jordan Belfi | John Marinelli | Nick | 2 | 2 |
| Kevin Rahm | Pastor Mark Rayburn | Mr. Duff | 1 | 1 |
| Todd Waring | Attorney George Hart | Tobin | 3 | 1 |
| Tyrees Allen | Patrick Liman | Dr. Saltzman | 3 | 1 |
| John Cothran, Jr. | Judge Horton | Ken Monroe | 3 | 2 |
| Cindy Drummond | Sally | Gwendolyn Yates, Louis' Wife | 1 | 2 |
| Eric Stoltz | Detective Chris Veeder | William Dunn | 3 | 3 |
| Nicholas Gonzalez | Detective Jonathan Ortiz | Clark West | 2 | 1 |
| Anne Ramsay | Roberta Richter | Wanda Gallagher | 3 | 1 |
| D.W. Moffett | Joseph Wright | Allan | 2 | 1 |
| Dennis Boutsikaris | Paul Ramont | Don Taylor | 2 | 1 |
| Joseph Lyle Taylor | Detective Vance | Weiss | 1 | 1 |
| Karly Rothenberg | Counselor #2 | Ruth Bennet | 1 | 1 |
| Keith Sellon-Wright | Psychiatrist | Surgeon #1 | 2 | 2 |
| Larry Sullivan | Nick Tursi | David Young | 1 | 1 |
| Linda Gehringer | Elise Waters | Georgia Fisher | 1 | 1 |
| Marshall Allman | Billy Hampton | Jeremy West | 1 | 2 |
| McNally Sagal | Attorney Briana Holden | Kari Donnelly | 1 | 5 |
| Robert Wisdom | Reverand Scofield | Mr. Hamilton | 1 | 1 |
| Leith Burke | Ron Deleon | Dr. McQueen | 2 | 2 |
| Audrey Wasilewski | Pam | Nicole Waldman | 2 | 1 |
| Bellamy Young | Sarah Paulson | Kathy | 1 | 2 |
| DaJuan Johnson | John Weathers | Barrett Bowlan | 1 | 2 |
| Annie Potts | Dr. Marla Dodds | Joyce Bosco | 1 | 1 |
| Dee Wallace | Joan Monroe | Joan Waring | 1 | 1 |
| Gary Basaraba | Randy Stevens | Micah | 1 | 1 |
| Joe Holt | Leonard Jackson | Steve Beck | 1 | 1 |
| Kevin Dunigan | Officer #2 | SWAT Guy | 1 | 1 |
| Meredith Salenger | Diane Walker | Daphne | 1 | 1 |
| Deborah Strang | Maxine Peters | Ellie Ratigan | 1 | 1 |
| Jessica Anne Bogart | Friend | Lindsay Colvin | 1 | 1 |
| John Getz | Maurice Hardin | Michael Breyers | 1 | 2 |
| Kari Coleman | Cheryl Swinger | Mother | 1 | 1 |
| Kathe Mazur | Judy Moran | Mrs. Epstein | 1 | 1 |
| Matthew Fahey | Ben Moran | Greg Bevell | 1 | 1 |
| Romy Rosemont | Detective Williams | Lea Seibert | 1 | 1 |
| Sarah Hagan | Patricia | Devo Friedman | 1 | 1 |
| Colleen Flynn | Jeannie Cooper | Nancy Mercer | 1 | 1 |
| Emil Beheshti | Paul Carlson | Man with Plaid Bow Tie | 1 | 1 |
| Jillian Bach | Colleen Ames | Gretchen | 1 | 1 |
| Jim Parrack | Joe Nelson | Ted Carr | 1 | 1 |
| Judith Moreland | Veronica Turmin | Mrs. Baer | 1 | 1 |
| Kristen Ariza | Lisa Gutenberg | Angela | 1 | 1 |
| Linara Washington | Cassandra | Gretchen McKay | 1 | 1 |
| Missy Yager | Kelly Bennet | Terri | 1 | 1 |
| Peter MacKenzie | Daryl Denham | Warren Kramer | 1 | 1 |
| Sharif Atkins | Greg Ogletree | Josh Greene | 1 | 1 |
| Spencer Garrett | Frank Barringer | Jim Walker | 1 | 1 |
| Tina Holmes | Caroline Cummins | Rebecca Bloom | 1 | 1 |
| James DuMont | Dave Simon | Sheldon Morris | 1 | 2 |
| John Bishop | Phil Swinger | James Carlson | 1 | 2 |
| Judith Hoag | Terry The Madam | Rhada Douglas | 1 | 2 |
| Amy Stewart | Darla Johnson | Diane Early | 1 | 1 |
| Ann Cusack | Martha Harris | Amy Polus | 1 | 1 |
| Austin Highsmith Garces | Hallway Reporter | Amber Courier | 1 | 1 |
| Betty Murphy | Mrs. Sherman | Lulu | 1 | 1 |
| Blue Deckert | Bailiff | Frank | 1 | 1 |
| Cheryl White | Karena Stratton | Lynn Connors | 1 | 1 |
| Erica Gimpel | Dr. Udell | Bethany Anderson | 1 | 1 |
| Gary Kraus | Man #2 | Louis Cardon | 1 | 1 |
| Isabella Hofmann | Kimberly Nelson | Irene Waller | 1 | 1 |
| Jayden Lund | Gary | Hulking Patient | 1 | 1 |
| Jos Viramontes | Reynolds | David Martinez | 1 | 2 |
| Larry Clarke | Brian Ford | Paul | 1 | 1 |
| Lee Garlington | Hannah Turley | Farah Linden | 1 | 1 |
| Michael Reilly Burke | Carl Middleton | Mr. Finch | 1 | 1 |
| Richard Roundtree | Cyrus Carter | Donald Burke | 1 | 1 |
| Shannon Cochran | Meredith | Mrs. Singleton | 1 | 1 |
| Stephanie Erb | Stephanie Davis | Mrs. Gantry | 1 | 1 |
| Steven Flynn | Russell Parks | Scott Robinson | 1 | 1 |
| Todd Babcock | Jeffrey Drake | Dr. Matthew Savoy | 1 | 1 |
| Yolanda Snowball | Alice | Physical Therapist | 1 | 1 |
| Keeshan Giles | Sam Malloy | Intern #3, Paramedic #2 | 1 | 3 |
| Amy Sloan | Joyce Birdseye | Kelly | 1 | 1 |
| Andrew James Allen | Artie Nelson | Coby McKee | 1 | 1 |
| Cyd Strittmatter | Elaine Bradley | Dr. Alicia Krause | 1 | 1 |
| David Clennon | Arthur Stanton | Jack Shandley | 1 | 1 |
| David Grant Wright | Richard Nelson | Mr. Burton | 1 | 1 |
| Devon Graye | Spencer Gordon | Brady Hauser | 1 | 1 |
| Don McManus | Cliff Reardon | Samuel Linden | 1 | 1 |
| John Allen Nelson | William Sheffield | Arthur Soltanoff | 1 | 1 |
| Karl T. Wright | Dr. Wolfe | Divorce Mediator | 1 | 1 |
| Michael Shamus Wiles | Detective Logan | Dr. Miller | 1 | 1 |
| Sterling Jones | Player #1 | Peter Martin | 1 | 1 |
| David Paluck | Public Defender | Surgeon #2 | 1 | 2 |
| Jeremiah Birkett | Roger | John McMurdo | 1 | 1 |
| Jill Remez | Medical Examiner | April's Examiner | 1 | 1 |
| Leslie Odom Jr. | Jordan Carter | PJ Walling | 1 | 1 |
| Scout Taylor-Compton | Grace Hendricks | Angie | 1 | 1 |
| Shelley Robertson | Carolyn Murphy | Arlene Travis | 1 | 1 |
| Alan Rachins | Judge Meyers | Louie | 1 | 1 |
| Jerry Kernion | Walt Golumbic | Bobby Corso | 1 | 1 |
| Liz Benoit | 911 Operator | Woman | 1 | 1 |
| Mark Fite | Fred Cooper | Jared Cassidy | 1 | 1 |
| Michael Mantell | Jesse Abrams | Tim Nolan | 1 | 1 |
| Pat Destro | Mrs. Tarnowski | Boise Nurse | 1 | 1 |
| Chet Grissom | Gary Wilson | Uncle Pat | 1 | 1 |
| Darlene Kegan | Rachel Grant | Ruby Walker | 1 | 1 |
| David Noroña | Mike Lisi | Dorian's Father | 1 | 1 |
| Elaine Kao | Newswoman | NICU Nurse | 1 | 1 |
| James Huang | Uniform | Social Worker | 1 | 1 |
| Rafael J. Noble | Kevin Grover | Roy Pepper | 1 | 1 |
| Richard Cox | Henry Brooks | Marvin | 1 | 1 |
| Rick Peters | Curt | Sean Greene | 1 | 1 |
| Trent Gill | Henry Wicks | David | 1 | 1 |
| Angelo Tiffe | Gene Raditzer | Trey Boyd | 1 | 1 |
| Dougald Park | Dr. Sutton | Lawyer | 1 | 1 |
| Lenora May | Nurse | Sheila | 1 | 1 |
| Sally Ann Brooks | Lisa Gilcrest | Marie Lamott | 1 | 1 |
| Sue Cremin | Carrie Barringer | Holly | 1 | 1 |
| William Charlton | Detective | Jeff | 1 | 1 |
| Amy Benedict | Cynthia | Nancy Temple | 1 | 1 |
| Helen Eigenberg | Ryan | Lillian Campion | 1 | 1 |
| John Sloman | Chris Bradley | Dr. Jordan Kinley | 1 | 1 |
| Sean Moran | Frank Karr | Lou Bradley | 1 | 1 |
| Andre Ware | Floyd Scarsdale | Dr. Evett | 1 | 1 |
| Francesca Ferrara | Irene | Anne | 1 | 1 |
| Rajni Kareer | Doctor | Mrs. Patel | 1 | 1 |
| Teddy Vincent | Neighbor #3 | Elderly Woman | 1 | 1 |
| Mickey Maxwell | Jason Myers | Minister | 1 | 1 |
← Close to Home × Grey's Anatomy
Cast data from TVmaze, licensed CC BY-SA 4.0.