All 53 actors in both ER and Prison Break
53 actors have appeared in both ER and Prison Break, across 419 episodes. The most-credited is Stacy Keach, Mike Gates in ER and Warden Henry Pope in Prison Break.
| Actor | In ER | In Prison Break | Eps | Eps |
|---|---|---|---|---|
| Stacy Keach | Mike Gates | Warden Henry Pope | 3 | 23 |
| Barbara Eve Harris | Sakina, Mrs. Kendrick | Felicia Lang | 3 | 20 |
| Reggie Lee | Christian | Bill Kim | 1 | 16 |
| Danny McCarthy | Firefighter James | Special Agent Danny Hale | 1 | 14 |
| Cress Williams | Officer Reggie Moore | Wyatt | 14 | 10 |
| Callie Thorne | Jodie Kenyon | Pamela Mahone | 4 | 7 |
| Silas Weir Mitchell | Luis, Marcus Hainey | Haywire | 2 | 11 |
| Shannon Lucio | Johanna Lambright | Trishanne | 1 | 10 |
| Stacy Haiduk | Impaled Mom | Lisa Tabak | 1 | 8 |
| Marina Benedict | Lois Landry | A&W | 1 | 6 |
| Camille Guaty | Mia | Maricruz Delgado | 1 | 9 |
| Matt DeCaro | Soccer Dad | Geary | 1 | 7 |
| Jeff Perry | Officer Mitch Palnick | Terrance Steadman | 1 | 3 |
| Michael Bryan French | Dr. MacGruder | Gregory White | 2 | 6 |
| Raphael Sbarge | Mr. Kirkendall | Ralph Becker | 2 | 6 |
| Tony Denison | Detective Patrie | Aldo Burrows | 1 | 5 |
| Michael O'Neill | Col. Ken Kilner | Herb Stanton | 1 | 3 |
| Kurt Caceres | Luis Sanchez | Hector | 1 | 5 |
| Tara Karsian | Liz Dade | Georgie | 7 | 1 |
| Marc MacAulay | Frank | Mr. Ives | 1 | 2 |
| Shaun Duke | Detective, Painter | Griffin Oren | 2 | 2 |
| José Zúñiga | Eduardo Lopez | Coyote | 2 | 2 |
| Jude Ciccolella | Roach Coach Charlie | Howard Scuderi | 1 | 3 |
| Steve Tom | MacPherson | Stuart Tuxhorn | 1 | 3 |
| Ryan Sands | Jeremy | Vincent Sandinsky | 1 | 1 |
| F.J. Rio | Miguel Rivas | Augusto | 1 | 2 |
| Ivar Brogger | Deposition Attorney | Vincent Sandinsky | 1 | 2 |
| Anthony Starke | Dr. Craig | Sebastian | 2 | 2 |
| Castulo Guerra | Judge Alter, Javier | General Zavala | 3 | 1 |
| Mark Pellegrino | Nathan Conley | Patrick Vikan | 1 | 2 |
| Michael Cudlitz | Lang | Corrections Officer Robert "Bob" Hudson | 1 | 2 |
| Troy Ruptash | Dave Fern | Jasper Potts | 1 | 2 |
| Adina Porter | Mrs. Hopkins | Leticia Barris | 1 | 2 |
| Keith Diamond | Det. Stetler | Tim Giles | 2 | 1 |
| Michael Gaston | U.S. Marshal Rick Cromley | Quinn | 1 | 2 |
| Mark Harelik | James | Marty Gregg | 1 | 1 |
| Andrew Rothenberg | Pauly Johnson | Sklar | 1 | 2 |
| David Franco | Dominic | Doctor | 1 | 1 |
| Michael McGrady | Fire Captain Davis | Captain Hutchinson | 1 | 1 |
| Romy Rosemont | Joanne Bairos | Det. Kathryn Slattery | 1 | 1 |
| Conor O'Farrell | Richard Abbott | Agent Miller | 2 | 1 |
| David Parker | Gary Sutton | Trucker | 1 | 1 |
| Keith Szarabajka | Mr. DeLuca | David Baker | 1 | 1 |
| Kirk B.R. Woller | Prisoner Transport Officer | Richard Sooter | 1 | 1 |
| Marshall Manesh | Babu | Nandu Banerjee | 1 | 1 |
| Michael Wiseman | Danny (Enforcer) | Det. Conor Mara | 1 | 1 |
| Sylva Kelegian | Donna | Denise | 1 | 1 |
| Linara Washington | Rena Carlson, Young Woman on Train | Jenae Conlin | 2 | 1 |
| David Clennon | Jared Morgan | Sen. Conrad Dallow | 1 | 1 |
| Roderick Peeples | The Butcher | Otto Fibonacci | 1 | 1 |
| Taylor Nichols | Mr. Adams | Dr. Erik Stammel | 1 | 1 |
| Christian Stolte | Driver | C.O. Stolte | 1 | 1 |
| Tab Baker | Vendor | Crab Simmons | 1 | 1 |
Cast data from TVmaze, licensed CC BY-SA 4.0.