All 62 actors in both ER and The Big Bang Theory
62 actors have appeared in both ER and The Big Bang Theory, across 610 episodes. The most-credited is Laura Cerón, Nurse Chuny Marquez in ER and Marta in The Big Bang Theory.
| Actor | In ER | In The Big Bang Theory | Eps | Eps |
|---|---|---|---|---|
| Laura Cerón | Nurse Chuny Marquez | Marta | 219 | 1 |
| Carol Ann Susi | Mrs. Clark | Mrs. Wolowitz | 1 | 39 |
| Kevin Sussman | Colin | Stuart Bloom | 2 | 25 |
| Sara Gilbert | Dr. Jane Figler | Leslie Winkle | 15 | 5 |
| Bob Newhart | Ben Hollander | Arthur Jeffries | 3 | 6 |
| Dean Norris | Bomb Specialist Clark | Colonel Williams | 1 | 6 |
| Vernée Watson | April Wilson | Althea | 2 | 5 |
| Alessandra Torresani | Kate Preston | Claire | 1 | 5 |
| Alice Amter | Dr. Miriam Nagarwala | Mrs. Koothrappali | 2 | 10 |
| Mark Harelik | James | Dr. Eric Gablehauser | 1 | 5 |
| Sara Rue | Jane | Dr. Stephanie Barnett | 1 | 3 |
| Michael Patrick McGill | Detective Ed Bernstein, Security #1, Officer Jeffries | Police Officer | 6 | 1 |
| Katee Sackhoff | Jason's Girlfriend | Katee Sackhoff | 1 | 2 |
| Lance Barber | Howard | George Cooper Sr., Jimmy Speckerman | 1 | 2 |
| Andrew Walker | Jack | Mike | 1 | 1 |
| Elizabeth Bogush | Debra Strickland | Dr. Catherine Millstone | 1 | 1 |
| Judy Greer | Tildie Mulligan | Dr. Elizabeth Plimpton | 1 | 1 |
| Kal Penn | Narajan | Dr. Campbell | 1 | 3 |
| Marcus Folmar | Foreman | Guard, Police Officer, Security Guard | 1 | 3 |
| Octavia Spencer | Maria Jones | Octavia | 1 | 1 |
| Annie O'Donnell | Eve | Mrs. Fowler, Mrs. Lorvis | 1 | 2 |
| Stacey Travis | Detective Weller | Sandy | 2 | 1 |
| Joe Manganiello | Officer Litchman | Joe Manganiello | 4 | 1 |
| Angela Sargeant | Shannon | Lana | 1 | 1 |
| Becky O'Donohue | Sophia | Siri | 1 | 1 |
| Eddie Shin | Med Student Stanley Mao | Dr. Park | 2 | 1 |
| Janelle Marra | Heather Tartaglia | Claire | 1 | 1 |
| Judith Moreland | Nurse Terry | Jan | 1 | 1 |
| June Squibb | Social Security Daughter | Meemaw | 1 | 1 |
| Ken Lerner | Harry Stopak, Stan Seidel | Dr. Schneider | 2 | 1 |
| Kevin Brief | Walter Brosnich | Glen, Security Guard | 1 | 2 |
| Michael Hyatt | Yvonne Devilliere | Charlotte | 1 | 1 |
| Michael Rapaport | Paul Canterna | Kenny Fitzgerald | 1 | 1 |
| Parvesh Cheena | Dr. Agbo | Marcus | 1 | 1 |
| Troy Winbush | Uniform Cop | Paramedic | 1 | 1 |
| Wayne Wilderson | Dr. Claypool | Travis | 1 | 1 |
| George Wyner | Rabbi | Dr. Zhang | 2 | 1 |
| David Barrera | Felix Hernandez | Officer Hernandez | 1 | 1 |
| Edward James Gage | Orderly | Mailman | 1 | 1 |
| Eileen Galindo | Heather Tocci | Letty | 1 | 1 |
| Jane Galloway Heitz | Pearl Gellin | Mildred | 1 | 1 |
| Jennifer Hale | Gloria | News Announcer | 1 | 1 |
| Josh Peck | Nick Stevens | Jesse | 1 | 1 |
| Karl T. Wright | Dr. Norris | Jimmy | 1 | 1 |
| Louise Claps | Mrs. Jenkins | Receptionist | 1 | 1 |
| Michael Dempsey | Mr. Beckwith | Security Guard | 1 | 1 |
| Peter Onorati | Officer Nick Napolitano | Angelo | 1 | 1 |
| Phil Abrams | Rodney | Dr. Bernstein | 1 | 1 |
| Rod Keller | Evan | Wardrobe Person | 1 | 1 |
| Ronald Hunter | Juror Two | Dan | 1 | 1 |
| Alison Martin | Mrs. Kendrick | Andrea | 1 | 1 |
| Cat Hammons | Counter Girl | Nurse | 1 | 1 |
| Lauri Johnson | Oncology Nurse | Mrs. Gunderson | 1 | 1 |
| Monica Garcia | Benita Escobar | Maria | 1 | 1 |
| Nicole J. Butler | Anesthesiologist | Clerk | 1 | 1 |
| Shane Blades | Marcus Udesky | Customer | 1 | 1 |
| Sharon Omi | Nurse Sulla | Nurse in Biohazard Suit | 1 | 1 |
| Ajgie Kirkland | Monty | Louie | 1 | 1 |
| Eric Nenninger | Psychotic Biting Patient | Neil | 1 | 1 |
| Jareb Dauplaise | Chris Hawkins | Jeff | 1 | 1 |
| Sergio Enrique | Cole | Son | 1 | 1 |
| Robert Noble | Santa | Older Gentleman | 1 | 1 |
Cast data from TVmaze, licensed CC BY-SA 4.0.