All 61 actors in both Grey's Anatomy and Lost
61 actors have appeared in both Grey's Anatomy and Lost, across 588 episodes. The most-credited is L. Scott Caldwell, Allison Cobb in Grey's Anatomy and Rose Nadler in Lost.
| Actor | In Grey's Anatomy | In Lost | Eps | Eps |
|---|---|---|---|---|
| L. Scott Caldwell | Allison Cobb | Rose Nadler | 1 | 20 |
| Sam Anderson | Michael Whitman | Bernard Nadler | 1 | 20 |
| Teresa Huang | Nurse Ruth | Surgeon | 19 | 1 |
| Jeff Perry | Thatcher Grey | Duckett | 15 | 1 |
| Michael Bowen | Roy Davis | Danny Pickett | 1 | 8 |
| Mark Pellegrino | Chris | Jacob | 1 | 7 |
| François Chau | Mr. Chue | Dr. Marvin Candle, Dr. Pierre Chang, Dr. Edgar Halliwax | 1 | 13 |
| Patrick Fischler | Jake Steiner | Phil | 1 | 8 |
| Eric Lange | Steven Tanner | Stuart Radzinsky | 1 | 6 |
| Marguerite Moreau | Dr. Emma Marling | Starla | 6 | 1 |
| Blake Bashoff | Elliott Meyer | Karl | 1 | 8 |
| Rachel Ticotin | Dr. Marie Cerone | Captain Teresa Cortez | 3 | 2 |
| Anthony Azizi | Syrian Doctor | Omar | 1 | 7 |
| Dylan Minnette | Ryan | David Shephard | 1 | 5 |
| April Grace | Greta's Sister | Bea Klugh | 1 | 4 |
| Tom Irwin | Officer Hancock | Dan Norton | 3 | 2 |
| Cynthia Watros | Mrs. Connor | Libby Smith | 1 | 2 |
| Mackenzie Astin | Danny Wilson | Tom Brennan | 2 | 1 |
| June Kyoto Lu | Sooyoung Oh | Mrs. Paik | 1 | 3 |
| Phil Abrams | Dr. Jim Nelson | Gellert | 3 | 1 |
| Zack Shada | Andy Michaelson | Young Liam | 2 | 2 |
| Billy Mayo | Rick | Kilo | 2 | 1 |
| Cheech Marin | Otis Sharon | David Reyes | 1 | 2 |
| Cleo King | Robin | Government Worker | 3 | 1 |
| Holland Roden | Gretchen Shaw | Emily | 1 | 1 |
| Marc Vann | Hematologist | Doctor | 1 | 4 |
| Robin Weigert | Karen Lawrence | Rachel Carlson | 1 | 2 |
| Ron Bottitta | Alex's Examiner | Leonard | 1 | 2 |
| Michelle Arthur | Brooke | Flight Attendant #3, Michelle | 1 | 3 |
| Dean Norris | Vince | Howard Gray | 2 | 1 |
| Matthew Alan | David Fisher | Cunningham | 1 | 1 |
| Raymond J. Barry | Gene Seers | Ray | 1 | 1 |
| Samantha Mathis | Melinda Prescott | Olivia | 3 | 1 |
| Saul Rubinek | Eli Rigler | Custody Attorney | 1 | 1 |
| Kevin Rankin | Jack Vaughan | Jerry | 2 | 1 |
| Faran Tahir | Isaac | Ishmael Bakir | 1 | 1 |
| John Walcutt | Paul Cotler | American Tourist | 1 | 1 |
| Lawrence Mandley | Chester Jones | Frainey | 1 | 1 |
| Mandy June Turpin | Karla | Florence | 1 | 1 |
| Marlene Forte | Carmen Delgado | Detective Mason | 2 | 1 |
| Michelle Forbes | Vicki Ann Rudin | Karen Decker | 1 | 1 |
| Monica Garcia | Peds Nurse | Nurse | 1 | 1 |
| Theo Rossi | Stan Giamatti | Sgt. Buccelli | 2 | 1 |
| Stephanie Niznik | Carol | Dr. Evelyn Ariza | 2 | 1 |
| Stephen Bishop | Firefighter | William Kincaid | 2 | 1 |
| Wendy Braun | Captain LeVantine | Gina | 1 | 2 |
| Geoffrey Rivas | Stu Vargas | Father Chuck | 1 | 1 |
| Rebecca Hazlewood | Dr. Mara Keaton | Nalini | 1 | 1 |
| Amy Stewart | Diane Early | Mother | 1 | 1 |
| Josh Randall | William | Nathan | 1 | 1 |
| Larry Clarke | Paul | customer | 1 | 1 |
| Madeline Carroll | Ivy Soltanoff | Annie | 1 | 1 |
| George Gerdes | Norman Sholman | Mr. Springer | 1 | 1 |
| Tim De Zarn | Santa Claus | Trevor | 1 | 1 |
| Traber Burns | Andy's Lawyer | Judge | 1 | 1 |
| Ammar Daraiseh | Aide | Hajer | 1 | 1 |
| Anthony Keyvan | Miguel Aranda | Young Sayid | 1 | 1 |
| James Huang | Social Worker | Chet | 1 | 1 |
| P.D. Mani | Anesthesiologist | Nabil | 1 | 1 |
| Colby French | Mr. Filson | Uncle Doug | 1 | 1 |
| John Henry Canavan | Stewart Tyler | Simon Pace | 1 | 1 |
Cast data from TVmaze, licensed CC BY-SA 4.0.