All 284 actors in both Grey's Anatomy and Shameless
284 actors have appeared in both Grey's Anatomy and Shameless, across 601 episodes. The most-credited is Michael Patrick McGill, Bob Corson in Grey's Anatomy and Tommy in Shameless.
| Actor | In Grey's Anatomy | In Shameless | Eps | Eps |
|---|---|---|---|---|
| Michael Patrick McGill | Bob Corson | Tommy | 1 | 90 |
| Scott Michael Campbell | Mr. Hubble | Brad | 1 | 38 |
| Isidora Goreshter | Paula | Svetlana Yevgenivna | 1 | 29 |
| Jeffrey Dean Morgan | Denny Duquette | Charlie Peters | 20 | 1 |
| Grace Rowe | Paramedic Grace | Dasha | 17 | 1 |
| Joe Adler | Dr. Isaac Cross | Milkovich Brother | 15 | 3 |
| Kerry O'Malley | Jane Collins | Kate | 1 | 17 |
| Tyler Jacob Moore | Dane Pinetti | Tony Markovich | 1 | 14 |
| Gloria Garayua | Dr. Graciella Guzman | Paramedic Laurie | 24 | 1 |
| Vanessa Bell Calloway | Lucinda Gamble | Carol Fisher | 2 | 23 |
| Rebecca Field | Sabine McNeil | Eliza | 7 | 5 |
| Emily Bergl | Trisha | Sammi Slott | 1 | 10 |
| Constance Zimmer | Dr. Alana Cahill | Claudia Nicolo | 5 | 5 |
| Jess Gabor | Tia Marwood | Kelly Keefe | 2 | 14 |
| June Squibb | Dr. Elsie Clatch | Etta Teasdale | 1 | 7 |
| Richard Flood | Dr. Cormac Hayes | Ford Kellogg | 9 | 6 |
| Nichole Sakura | Leanne | Amanda | 1 | 17 |
| Marguerite Moreau | Dr. Emma Marling | Linda | 6 | 5 |
| Ever Carradine | Athena | Erika | 1 | 4 |
| Joel Murray | ICE Agent Martin Fields | Eddie Jackson | 1 | 9 |
| Joy Osmanski | Intern Lucy | Dr. Kwan | 11 | 3 |
| Kate Miner | Mindy Wallace | Tami Tamietti | 1 | 9 |
| Rebecca Metz | Brenda Lawson | Melinda | 1 | 11 |
| Maile Flanagan | Tech | Connie | 4 | 6 |
| Sharon Lawrence | Robbie Stevens | Margo | 1 | 6 |
| Pej Vahdat | Tarik Amin | Kash | 1 | 8 |
| Juliette Angelo | Danielle | Geneva | 1 | 10 |
| Caroline Clay | Cece Colvin | Judge Cheryl Ward | 7 | 1 |
| Joshua Malina | Seth Hammer | Arthur Tipping | 1 | 5 |
| Mary Kay Place | Olive "Ollie" Warner | Oopie Tamietti | 3 | 3 |
| Sumalee Montano | Lena McCallister | Turks | 1 | 1 |
| Lynn Chen | Dr. Michelle Lin | Mimi | 5 | 2 |
| Michael Reilly Burke | Mr. Finch | Theo Wallace | 1 | 6 |
| Brent Sexton | Jerry Frost | Patrick Gallagher | 1 | 2 |
| Dennis Boutsikaris | Don Taylor | Professor Hearst | 1 | 5 |
| Mackenzie Astin | Danny Wilson | Tyler | 2 | 1 |
| Mike McColl | Paul Castello | ICE Agent | 2 | 1 |
| Morgan Lily | Jennifer "Jenny" Parker | Bonnie | 2 | 4 |
| Rose Abdoo | Dr. Dawson | Dr. Vega | 1 | 2 |
| Russell Hornsby | Digby Owens | Tony's Partner | 1 | 2 |
| Catfish Jean | Jermaine Talbott | Tire Neck | 3 | 1 |
| Pat Healy | Tom Russell | Bar Patron | 2 | 2 |
| Phil Abrams | Dr. Jim Nelson | Mr. Bancroft | 3 | 1 |
| Annie Sertich | Peggy Knox | Sorority Matron | 3 | 2 |
| Stacey Oristano | Nurse Frankie Shavelson | Trina | 3 | 2 |
| Chelsea Alden | Danielle Gordon | Tish | 1 | 3 |
| Cleo King | Robin | Registrar | 3 | 1 |
| Jane Galloway Heitz | Annie's Mother | Claire | 1 | 1 |
| Lisa Vidal | Dr. Alma Ortiz | Maria Vidal | 3 | 2 |
| Mac Brandt | Paramedic #3 | Sgt. Ruger | 4 | 1 |
| Michael Hyatt | Mariann Davidson | Officer Pimental | 1 | 1 |
| Omid Abtahi | Aasif | Sameer | 1 | 1 |
| Patrick Fischler | Jake Steiner | Wade Shelton | 1 | 2 |
| Shannon Lucio | Amanda | Alison de Marco | 3 | 1 |
| Thomas Barbusca | Link McNeil | Remedial Kid | 5 | 1 |
| Wallace Langham | Dr. Steve Corridan | Dr. Tyson | 1 | 2 |
| Wayne Lopez | Paramedic #2 | Wyatt | 4 | 2 |
| Will Sasso | Jet / Maintenance Worker | Yanis | 2 | 4 |
| William Leon | Gary Walton | Raul | 1 | 1 |
| Martin Yu | Anesthesiologist, Resident, CT Tech | Jonas | 6 | 1 |
| Jenica Bergere | Kimberly "Kiki" Thompson | Lisa | 1 | 5 |
| Ed Lauter | Timothy Miller | Dick Healey | 1 | 4 |
| Idara Victor | Amelie Ward | Sarah | 1 | 4 |
| Izabella Alvarez | Hope Daniels | Sarah | 1 | 4 |
| Hilda Boulware | Ante Ndugu | Marsha | 3 | 1 |
| Alex Alexander | Annie Connors | Stella | 1 | 2 |
| Arden Myrin | Kirsten | Dollface Dolores | 1 | 5 |
| Brenda Banda | Diana Cortez | Doris | 1 | 2 |
| Christian Clemenson | Ivan Fink | Christopher Collier | 1 | 2 |
| Dan Martin | Scott Hill | Officer Jones | 2 | 1 |
| Elizabeth Bond | Kimmie Kepner | Elena | 2 | 1 |
| John Billingsley | Jacob Nolston | Dr. Drew | 2 | 1 |
| Merrin Dungey | Dr. Naomi Bennett | Frank’s Nurse | 2 | 1 |
| Oscar Peña | Jose Lopez | Jorge | 2 | 1 |
| Skye P. Marshall | Mary Hodges | June | 1 | 2 |
| Alex Désert | Miles Green | Union Jerry | 1 | 1 |
| Camille Chen | Kerry Schultz | Lewis | 1 | 1 |
| David Bowe | Don | Bob Tamietti | 1 | 5 |
| Jack Axelrod | Really Old Man, Charlie Yod | Old Guy | 3 | 1 |
| Lisseth Chavez | Kate Endris | Marita | 1 | 1 |
| Sunkrish Bala | Steve Murphy | Andy | 1 | 3 |
| Jillian Armenante | Mindy Carlson | Abby Ruggiero | 2 | 1 |
| Paula Andrea Placido | Irene Montoya | Calista | 1 | 2 |
| Rueben Grundy | Jake | Cox | 2 | 1 |
| Shakira Barrera | Young Mom | Heidi Cronch | 1 | 2 |
| Sharif Atkins | Josh Greene | Peter Naylor | 1 | 2 |
| Stacy Edwards | Kathleen Wheeler | Laura Shelton | 1 | 2 |
| Susan Chuang | Naomi Evans | Dr. Kathy Beard | 1 | 2 |
| Suzanne Cryer | Caroline Klein | Cheryl | 1 | 2 |
| Alyssa Gabrielle Rodriguez | Phoebe Moss | Jennie | 2 | 2 |
| Carlease Burke | Mrs. Gates | Roberta | 1 | 3 |
| Jeff Doucette | Warren Sterman | Uncle Matt | 2 | 2 |
| Stacie Greenwell | Mrs. Vanderburg | Olga | 1 | 4 |
| Steven M. Gagnon | Mr. Lepik | Bill Pratt | 1 | 4 |
| A. Russell Andrews | Mr. Davis | Lance | 1 | 1 |
| Alan Blumenfeld | Shawn Sullivan | Neil | 1 | 1 |
| Bre Blair | Lauren Pailey | Cynthia | 1 | 1 |
| Brent Jennings | Charles Redford | Principal Monroe | 1 | 2 |
| Brit Morgan | Erica Marsh | Lucy Jo Heisner | 1 | 1 |
| Caroline Choi | Laura Young | Sister Frances | 1 | 3 |
| Casey Thomas Brown | Keith | Alan | 1 | 1 |
| Emy Coligado | Janelle Duco | Wesley Gretsky | 1 | 1 |
| Faran Tahir | Isaac | Adeeb | 1 | 1 |
| Francesca P. Roberts | Mrs. Bird | Ms. Taylor | 1 | 1 |
| Jason Antoon | Mr. Samuels | Dr. Ruben | 1 | 1 |
| June Carryl | Nurse | Beatrice | 1 | 1 |
| Karl T. Wright | Divorce Mediator | Alderman Jenkins | 1 | 1 |
| Lisa Waltz | Margot Billings | Mrs. Sugar | 1 | 1 |
| Omar Leyva | Luis Rivera | Federale | 3 | 1 |
| Paul Dooley | Dr. Walter Tapley | Ralph | 1 | 2 |
| Steven M. Porter | Joey | Craig | 1 | 3 |
| Nadine Ellis | Melissa Walker | Dr. Brenda Williams | 1 | 3 |
| Délé Ogundiran | Nurse Terri Akumbu | Khadija Okafur | 1 | 2 |
| Lori Alan | Ellen Weaver | Stacy Baer | 1 | 2 |
| Antonio D. Charity | Michael Nelson | Duncan | 1 | 1 |
| Barry Shabaka Henley | Mr. Patterson | Judge Glen Aufseeser | 1 | 1 |
| Carol Locatell | Mai | Eleanor Wyman | 1 | 1 |
| Charlie Bodin | Todd | Shep | 1 | 1 |
| Christopher Rivas | Rodney | Eduardo | 1 | 1 |
| Collette Wolfe | Karin Taylor | Tessa | 1 | 1 |
| David DeLuise | Charlie Connor | Proctor | 1 | 1 |
| Drew Rausch | John Finch | Sgt. Benz | 1 | 1 |
| Ellen Wroe | Mrs. Green | Clancy | 1 | 1 |
| Gina Hecht | Mrs. Sutton | Rachel | 1 | 1 |
| James Earl | Evan | Detective Hightower | 1 | 1 |
| Jan Hoag | Wheezing Patient | Sister Ann Halloran | 1 | 1 |
| Kate Cobb | Mari Prishna | Jane Pratt | 1 | 3 |
| Kimberly Hébert Gregory | Deborah Curzon | Nurse | 1 | 1 |
| Lela Lee | Mrs. Richardson | Lenore | 1 | 1 |
| Linara Washington | Gretchen McKay | Benyon | 1 | 1 |
| Maz Jobrani | Dakhir Hamed | Dr. Johnny | 1 | 1 |
| Paul James | Eric | T.A. | 1 | 1 |
| Susan Ruttan | Mrs. Swore | Sister Mary Luke | 1 | 1 |
| Tommy O'Brien | Young Alex Karev | Alex | 1 | 1 |
| Betsy Baker | Barb | Janice | 1 | 2 |
| Bruce Beatty | Jerry Hoffman | Jim | 2 | 1 |
| Cheyenne Haynes | Mindy | Bethany | 2 | 1 |
| John Bishop | James Carlson | Max | 2 | 1 |
| John Duerler | Grant | Officer Cody | 2 | 1 |
| Madison Leisle | Lisa the Child | Ashley | 2 | 1 |
| Andrew Borba | Chris Ward | Officer Hahn | 1 | 1 |
| Bayne Gibby | Cheryl Giles | Mallory | 1 | 1 |
| Gina Gallego | Lucia Torres | Dr. Martha Nutig | 1 | 1 |
| Irene Choi | Ashley | Taryn | 1 | 1 |
| Jayden Lund | Hulking Patient | Scott | 1 | 1 |
| Johnny Sneed | Garrett | Richard | 1 | 2 |
| Jonathan Goldstein | Ken May | Winston | 1 | 1 |
| Jos Viramontes | David Martinez | Phil | 2 | 1 |
| Judith Moreland | Mrs. Baer | Jolene | 1 | 1 |
| Karen Maruyama | Lisa Saito | Dr. Ma | 1 | 2 |
| Larry Clarke | Paul | Timothy | 1 | 1 |
| Mary Pat Gleason | Marge Walker | Drug Test collector | 1 | 1 |
| Mike Hagerty | Al Keller | Ron | 1 | 2 |
| Richard Portnow | Saul | Johnny Boxcars | 1 | 1 |
| Sandy Martin | Sally | Doctor | 2 | 1 |
| Shane Paul McGhie | Eddie Oliver | Jude Toussaint | 1 | 1 |
| Tina Huang | Roxanne | Yvonne | 1 | 1 |
| Billy Mayo | Rick | Dispatch | 2 | 1 |
| Brett Rickaby | Mr. Weston | Bruno | 1 | 2 |
| Noel Arthur | Deputy Fire Chief | Bouncer | 2 | 1 |
| Abbie Cobb | Francis "Frankie" Keller | Colette | 1 | 1 |
| Audrey Wasilewski | Nicole Waldman | Ann Matlock | 1 | 1 |
| Charlene Amoia | Dr. Kate Lachman | Audrey | 1 | 1 |
| Christine Horn | Ericka | Robia | 1 | 1 |
| Cloie Wyatt Taylor | Annie Cooper | Samantha | 1 | 1 |
| Erik Audé | Paramedic Jonathan | Drug Cop | 1 | 1 |
| Henry G. Sanders | Dr. Hudson | Jelly | 1 | 1 |
| J.P. Manoux | Danny Nelstadt | Zach | 1 | 1 |
| JoNell Kennedy | Duda Kyat | Doctor | 1 | 1 |
| Josh Clark | Lenny Shulte | Tacker | 1 | 1 |
| Nancy Youngblut | Donna Mae Clarkson | Mrs. Kandage | 1 | 1 |
| Peggy Dunne | Louise | Pamela | 1 | 1 |
| Rosalind Chao | Kathleen Patterson | Doctor | 1 | 1 |
| Sonya Leslie | Rita | Keandra | 1 | 1 |
| Stephanie Czajkowski | Firefighter Carroll | Patty | 1 | 1 |
| Wilson Cruz | Kyle | Bartender | 1 | 1 |
| Candace Brown | Milo | Alana Murphy | 1 | 2 |
| Kelli Kirkland Powers | Claire | Kim | 2 | 1 |
| Adam Kulbersh | Tommy | Bank Manager | 1 | 1 |
| Alina Phelan | Karen Marks | Florist | 1 | 1 |
| Brandon Black | Jeremy | Flavio | 1 | 1 |
| Brandon Claybon | Dante Collier | Andrew | 1 | 1 |
| Carla Vila | Angela | Kendra | 1 | 1 |
| Cathryn de Prume | Mrs. Nash | Hilary | 1 | 1 |
| Chiquita Fuller | Ashley Wright | Yolanda | 1 | 1 |
| Gavin Houston | Ed Benson | Officer Paul Sikes | 1 | 1 |
| Greg Linington | Applicant #3 | Craig Jeffries | 1 | 1 |
| Jes Macallan | Hillary | Tammy | 1 | 1 |
| Jin Maley | Reporter #1 | Makayla | 1 | 1 |
| Katherine Cunningham | Ashley | Danielle | 1 | 1 |
| Kelvin Brown | Frankie | Campus Cop 2 | 1 | 1 |
| Lex Medlin | Byron Gibbis | Dr. Jonathan Rosenbaum | 1 | 1 |
| Lisa Long | Marlene D. | Scotty | 1 | 1 |
| Mark Berry | AA Member | Cop Julius | 1 | 1 |
| Martha Boles | Lisa Pollock | Ellen | 1 | 1 |
| Mia Barron | Lauren Turner | Liz | 1 | 1 |
| Micah Cohen | Glen | Jeff Murphy | 1 | 2 |
| Paul Cassell | John Hanson | Quinton Fleet | 1 | 1 |
| Celia Finkelstein | Nurse Bridget Irving | Dawn | 2 | 1 |
| Keith Sellon-Wright | Surgeon #1 | Joe | 2 | 1 |
| Roberta Bassin | Trial Patient #4 | Mrs. Winston | 1 | 2 |
| Amanda Payton | Dr. Daphne Lopez | Flavia | 1 | 1 |
| Brian Scolaro | Mike | Baxter | 1 | 1 |
| Charles Emmett | Mr. Bosson | Dr. Carter | 1 | 1 |
| Cher Álvarez | Mariana | Quinn | 1 | 1 |
| Chriselle Almeida | Jaclyn Werlein | Donna | 1 | 1 |
| Desean Terry | Colin Cooke | Ron | 1 | 1 |
| Jaime Alvarez | Suited Man | Worker | 1 | 1 |
| Janet Song | Desk Worker | Korean Woman | 1 | 1 |
| Jee Young Han | Ingrid | Scarlet | 1 | 1 |
| John Churchill | Charlie | Skip | 1 | 1 |
| Joni Bovill | Dr. Marks | Desk Nurse | 1 | 1 |
| Matt McTighe | Vincent Wagner | Clint | 1 | 1 |
| Michael Mantell | Tim Nolan | Dean Wheeler | 1 | 1 |
| Susan Berger | Lee | Donnie | 1 | 1 |
| Carol Mansell | Veronica | Mrs. Teasley | 1 | 1 |
| Corey Craig | Brian Danzinger | Carsten | 1 | 1 |
| Dale Dickey | Emily "Gasoline" Bennett | Aunt Ronnie | 1 | 1 |
| Gary Kraus | Louis Cardon | Mike | 1 | 1 |
| Heather McComb | Rachel Burke | Wendy | 1 | 1 |
| Kathryn Taylor Smith | Nurse Caroline | Dr. Lawrence | 1 | 1 |
| Liz Jenkins | Guard #3 | Bertha | 1 | 1 |
| Maria McCann | Renee | Diane | 1 | 1 |
| Sally Ann Brooks | Marie Lamott | Lucy | 1 | 1 |
| Susan Grace | Jane | Mrs. Joyce | 1 | 1 |
| Angelo Tiffe | Trey Boyd | Gary | 1 | 1 |
| Christopher Guyton | Big Foot | Shelby | 1 | 1 |
| Cici Lau | Trial Partner #1 | Mariella | 1 | 1 |
| Jack Landron | Chaplain | Howard | 1 | 1 |
| James Moses Black | Duncan | CNA | 1 | 1 |
| Jessica Rosilyn | Nurse Georgia | Dee Sanders | 1 | 1 |
| Sharon Omi | Worried Tenant | Nurse | 1 | 1 |
| Sonia Jackson | Patient #1 | Darla Martini | 1 | 1 |
| Tim De Zarn | Santa Claus | Nana | 1 | 1 |
| Wyatt Walter | Vaughn Bishop | Chet | 1 | 1 |
| Avery Clyde | Elyse | Madison | 1 | 1 |
| Jarrod Crawford | Dr. Oslow | Sallow Parent | 1 | 1 |
| Steve Hasley | Aaron Marshall | Dr. Thompson | 1 | 1 |
| Tonja Kahlens | Courtney Swanson | Lois | 1 | 1 |
| Andrew Carrillo | Bill | Tony Casas | 1 | 1 |
| Harrison Xu | Gerard | Ralph Wong | 1 | 1 |
| John Bain | Savant Interviewee | Brooks | 1 | 1 |
| Jonathan Erickson Eisley | Bartender | Hippie Dad | 1 | 1 |
| Kirk Bovill | Brian Turner | Darren | 1 | 1 |
| Regina Bryant | Lacey | Becca | 1 | 1 |
| Vince Cefalu | ND Patient | Cop Lenny | 1 | 1 |
| Daniel Kash | Executive Two | Russian | 1 | 1 |
| Greta Sesheta | Shayna | Tessie Thompson | 1 | 1 |
| Joshua Wolf Coleman | Lawyer | Dr. Emmanuel Garcia | 1 | 1 |
| Michael Sasaki | Ken Bendix | Tim | 1 | 1 |
| Thomas F. Duffy | The Hammer | Tommy | 1 | 1 |
| Amir M. Korangy | Dr. Safavi | Rami | 1 | 1 |
| Sheila Shaw | Michelle Begler | Church Woman | 1 | 1 |
| Sloan Robinson | Tabitha | Sally | 1 | 1 |
| Stacey Moseley | Donna | Candace | 1 | 1 |
| Amber Friendly | Photographer | Alonso | 1 | 1 |
| Angela Landis | Flight Attendant | Christa | 1 | 1 |
| Anton Narinskiy | Gunnar | Boone | 1 | 1 |
| Jaylee Chen | Woman | Liyuan | 1 | 1 |
| John Deignan | Vincent Freeman | Howie | 1 | 1 |
| Arianna Ortiz | Jessica Schoman | Principal Colon | 1 | 1 |
| Cathrine Grace | Trial Patient #6 | Woman | 1 | 1 |
| Chet Grissom | Uncle Pat | Vernon | 1 | 1 |
| Lisa Linke | Melissa Gailis | Netta | 1 | 1 |
| Raff Anoushian | Cabbie | Foreman | 1 | 1 |
| Cal Gibson | Larry Keys | Mr. Johnson | 1 | 1 |
| Chelsea Marie Davis | Lilah | Jojo | 1 | 1 |
| Devyn Placide | Truman | Bob | 1 | 1 |
| Elyse Dinh | Kathleen | Tram | 1 | 1 |
| Eve Sigall | Old Lady | Older Woman | 1 | 1 |
| Jonathan Dane | Michael Fazioli | Sully | 1 | 1 |
| Michael Hagiwara | Charles Hyatt | Mr. Dunkel | 1 | 1 |
| Ren Hanami | Mrs. Chen | Judge Manija Abbasi | 1 | 1 |
| Ron Butler | Jordan Shouse | Advisor | 1 | 1 |
| Carl Gilliard | Older Tenant | Albert | 1 | 1 |
| Ingrid Walters | Nurse Vivian | Salma | 1 | 1 |
| John-Patrick Driscoll | Customs Officer | Ross | 1 | 1 |
| Patti Tippo | Cindy Thomas | Annie | 1 | 1 |
| Ed Ackerman | Eyeball Man | Asst. DA McClatchy | 1 | 1 |
| Lisa Costanza | Anna Anderson | Carmen | 1 | 1 |
| Mashari Bain | Ava Krug | Sue | 1 | 1 |
| Antonio Roccucci | Brad DiMarco | Passerby | 1 | 1 |
| Raymond Forchion | Minister | Minister | 1 | 1 |
| Hymnson Chan | Hotel Employee | Sam | 1 | 1 |
Cast data from TVmaze, licensed CC BY-SA 4.0.