Actors in both Grey's Anatomy and Two and a Half Men
100 actors have appeared in both Grey's Anatomy and Two and a Half Men, across 729 episodes. The most-credited is Chris O'Donnell, Finn Dandridge in Grey's Anatomy and Bill in Two and a Half Men.
| Actor | In Grey's Anatomy | In Two and a Half Men | Eps | Eps |
|---|---|---|---|---|
| Chris O'Donnell | Finn Dandridge | Bill | 10 | 1 |
| Rebecca McFarland | Tara Parker | Leanne | 2 | 8 |
| John O'Brien | Lab Tech Jeffrey | Waiter | 13 | 1 |
| Deanna Russo | Nola Marques | Laurel | 2 | 3 |
| Joel Murray | ICE Agent Martin Fields | Petey, Doug, Nick | 1 | 4 |
| Katherine LaNasa | Kalpana Vera | Lydia | 1 | 4 |
| Missi Pyle | Dr. Nicole Baylow | Delores Pasternak | 1 | 4 |
| Coby Ryan McLaughlin | Chad Anderson | Jeremy | 1 | 2 |
| Kimberly Quinn | Reena Thompson | Donna | 1 | 2 |
| Annie Potts | Joyce Bosco | Lenore | 1 | 1 |
| Darryl Sivad | Justice of the Peace | Cab Driver | 1 | 1 |
| David Denman | Rick Jacobs | Jack | 1 | 1 |
| Dylan Minnette | Ryan | Little Charlie | 1 | 1 |
| Jen Lilley | Kara Fisher | Bridesmaid #4 | 1 | 1 |
| Kimberly Hébert Gregory | Deborah Curzon | Lisa | 1 | 1 |
| Lee Garlington | Farah Linden | Peggy | 1 | 1 |
| Marion Ross | Betty Donahue | Margaret | 1 | 1 |
| Myndy Crist | Diane Hanson | Wendy | 1 | 1 |
| Paulina Olszynski | Lisa | Trudy | 1 | 1 |
| Stephanie Erb | Mrs. Gantry | Mrs. Schmidt | 1 | 1 |
Cast data from TVmaze, licensed CC BY-SA 4.0.