All 116 actors in both Grey's Anatomy and Will & Grace
116 actors have appeared in both Grey's Anatomy and Will & Grace, across 713 episodes. The most-credited is Steven W. Bailey, Joe in Grey's Anatomy and Vin in Will & Grace.
| Actor | In Grey's Anatomy | In Will & Grace | Eps | Eps |
|---|---|---|---|---|
| Steven W. Bailey | Joe | Vin | 30 | 1 |
| Geena Davis | Dr. Nicole Herman | Janet Adler | 13 | 1 |
| Kali Rocha | Dr. Sydney Heron | Stephanie | 11 | 1 |
| Winston Story | Dr. Leo Byrider | Rex | 20 | 1 |
| John O'Brien | Lab Tech Jeffrey | Man, Salesperson | 13 | 2 |
| Debra Mooney | Evelyn Hunt | Sister Robert | 13 | 1 |
| Patrick Dempsey | Dr. Derek Shepherd | Matthew Moshea | 4 | 3 |
| Taye Diggs | Dr. Sam Bennett | James Hansen | 3 | 4 |
| Demi Lovato | Hayley May | Jenny | 1 | 4 |
| Mary Pat Gleason | Marge Walker | Bridget, Sally | 1 | 4 |
| Ryan Pinkston | Carlton Allyn | Officer Drew | 1 | 4 |
| Brent Sexton | Jerry Frost | Guard | 1 | 2 |
| Ever Carradine | Athena | Pam | 1 | 2 |
| Joy Osmanski | Intern Lucy | Trish Yashida | 11 | 1 |
| Raphael Sbarge | Paul | Alex | 2 | 1 |
| Veronica Cartwright | Lydia Ashford | Judith McFarland | 2 | 1 |
| Emily Rutherfurd | Nancy Karev | Joanne | 1 | 4 |
| Mackenzie Marsh | Val Ashton | Angela | 3 | 2 |
| Erinn Hayes | Cathy Becker | Katherine Fallon | 1 | 1 |
| Ivar Brogger | Graham Cunningham | Mr. Hutt | 1 | 1 |
| Ken Marino | Brad Ackles | Mark | 1 | 1 |
| Mark Harelik | Keith Polus | Tim | 1 | 3 |
| T.R. Knight | Dr. George O'Malley | Dexter Murphy | 1 | 1 |
| Todd Stashwick | Mr. Kramer | Gabe Robinson | 1 | 1 |
| Christopher Thornton | Daniel Campbell | Luke | 1 | 2 |
| Dan Bucatinsky | Jeffrey | Neil | 1 | 2 |
| Patrick Fabian | Dr. Oliver Lebackes | Alan | 2 | 1 |
| Rosanna Arquette | Constance Ferguson | Julie | 1 | 2 |
| Tom Verica | Michael Norris | Danny | 1 | 2 |
| Keeshan Giles | Intern #3, Paramedic #2 | Hector | 3 | 1 |
| Adam Lazarre-White | Oncology Resident | Manager | 1 | 1 |
| Amy Farrington | Mary May | Phyllis | 1 | 1 |
| Andy Favreau | Jack Moss | JJ Wise | 1 | 1 |
| Brian Howe | Robert Fischer | Ken | 1 | 1 |
| Brooke Baumer | Obstetrician | Alex, Woman | 1 | 2 |
| Corinne Bohrer | Emma Correa | Judy | 1 | 1 |
| Eric Stoltz | William Dunn | Tom Cassidy | 3 | 2 |
| Gina Hecht | Mrs. Sutton | Amy | 1 | 1 |
| Hal Linden | Bertram "Bertie" Hollister | Alan | 1 | 1 |
| Hallee Hirsh | Claire | Olivia Walker | 2 | 1 |
| J.P. Manoux | Danny Nelstadt | Minion | 1 | 1 |
| Jamie-Lynn Sigler | Dr. Laura Kaplan | Ro | 1 | 2 |
| Judith Ivey | Barbara Robbins | Eleanor Markus | 1 | 3 |
| Karen Bankhead | Georgia | Burnadean | 1 | 1 |
| Kathryn Joosten | Mrs. Drake | Felicia | 1 | 1 |
| Larry Sullivan | David Young | Robert | 1 | 1 |
| Lee Garlington | Farah Linden | Annette | 1 | 2 |
| Markus Flanagan | Ed Hamilton | Dr. Loranger | 1 | 1 |
| Matt Crabtree | IDC Dude | Stage Manager | 1 | 2 |
| Rose Abdoo | Dr. Dawson | Aunt Rita | 1 | 1 |
| Sara Gilbert | Kim Allen | Cheryl | 1 | 1 |
| Scott Haven | Randy Begler | Steve | 1 | 1 |
| Seth Green | Nick Hanscom | Randall Finn | 2 | 1 |
| Stephanie Faracy | Mrs. Sullivan | Nurse Eva | 1 | 1 |
| Steve Hasley | Aaron Marshall | Carlo, Clerk | 1 | 2 |
| Sunkrish Bala | Steve Murphy | Gerald | 1 | 1 |
| Todd Robert Anderson | Harold Peters | Kurt | 1 | 1 |
| Joyce Guy | Ms. Henry | Lynette | 3 | 1 |
| Bernadette Peters | Sarabeth Breyers | Virginia | 2 | 1 |
| Sara Paxton | Leticia Gregory | Melanie | 2 | 1 |
| Yvans Jourdain | Businessman | Jon | 2 | 1 |
| Bob Rumnock | ND Doctor | Salesman | 1 | 1 |
| Eileen Fogarty | Mrs. Chen's Sister | Hostess | 1 | 1 |
| Emil Beheshti | Man with Plaid Bow Tie | Mike | 1 | 1 |
| Helen Slater | Nadia Shelton | Peggy Truman | 1 | 1 |
| Jennifer Aspen | Elaina | Sarah | 1 | 1 |
| Jim Ortlieb | Jack O'Brien | Ira | 1 | 1 |
| Karl T. Wright | Divorce Mediator | Wayne | 1 | 1 |
| Kathleen Wilhoite | Leslie Goldman | Sally | 1 | 1 |
| Lela Lee | Mrs. Richardson | Ping | 1 | 1 |
| Lori Alan | Ellen Weaver | Jean | 1 | 1 |
| Mark Cirillo | Mr. Holmes | Contestant | 1 | 1 |
| Meredith Salenger | Daphne | Lucy | 1 | 1 |
| Peter Paige | Benjamin O'Leary | Roger O'Neil | 1 | 1 |
| Shohreh Aghdashloo | Dr. Helen Crawford | Pam | 1 | 1 |
| Walter Addison | Chief Martin Vance | D.T. Petersen | 1 | 1 |
| Mitch Silpa | Tim Ruggles | Maitre D' | 2 | 1 |
| Aaron Lustig | Judge William Benson | Marv Buhl | 1 | 1 |
| Brian Michael Jones | Fish Man | Joe | 1 | 1 |
| Jere Burns | Ben Bosco | Man In Cast | 1 | 1 |
| Jet Jurgensmeyer | Jack Hobart | Skip | 1 | 1 |
| Kevin Brief | Barry Taylor | Ralph | 1 | 1 |
| Lee Majors | Chuck Cain | Burt Wolfe | 1 | 1 |
| Michael Merton | Dexter | Maitre d' | 1 | 1 |
| Peter MacKenzie | Warren Kramer | Mean Guy | 1 | 1 |
| Rebecca Lowman | Mrs. James | Pamela | 1 | 1 |
| Stephen Spinella | Malar Pascowitz | Bret | 1 | 1 |
| Wayne Wilderson | Bill Adams | Ellis Palmer-Payne | 1 | 1 |
| Kelli Kirkland Powers | Claire | Mona | 2 | 1 |
| Raymond Forchion | Minister | Clayton | 1 | 2 |
| Aly Mawji | Dr. Russell | Liam | 1 | 1 |
| Antonio D. Charity | Michael Nelson | Male Officer | 1 | 1 |
| Barry Livingston | Wayne Sheehan | Vince | 1 | 1 |
| Charles Emmett | Mr. Bosson | Luke | 1 | 1 |
| Cheryl White | Lynn Connors | Cheryl Bricker-Fossberg | 1 | 1 |
| Drew Lipson | Corey | Baseball Player | 1 | 1 |
| Eva La Dare | Police Officer #2 | Dr Welch | 1 | 1 |
| Gerald Downey | Dr. Kenton Giles | Student Nurse Clark | 1 | 1 |
| Gregor Manns | Levi Johnson | Customer | 1 | 1 |
| Helen Eigenberg | Lillian Campion | Vicky | 1 | 1 |
| James Huang | Social Worker | Male Passenger | 1 | 1 |
| Lainie Kazan | CJ | Aunt Honey | 1 | 1 |
| Mickey Maxwell | Minister | Doctor | 1 | 1 |
| Nealla Gordon | Jill Boyd | Eileen | 1 | 1 |
| Pej Vahdat | Tarik Amin | Steve | 1 | 1 |
| Robbie Troy | Mrs. Bryce | Candy | 1 | 1 |
| Sara Van Horn | Nash's Grandma | Woman | 1 | 1 |
| Amari O'Neil | Max Forrester | Felix | 1 | 1 |
| Devere Rogers | Lunch Server | Owen | 1 | 1 |
| Fareed Ward | Captain Bruno | Guy #1 | 1 | 1 |
| Karen Y. McClain | Reaves | Ruth | 1 | 1 |
| Stephanie Erb | Mrs. Gantry | Mona | 1 | 1 |
| Wendy Schenker | Nervous Tenant | Woman #1 | 1 | 1 |
| Michael Medico | Martin | Josh | 1 | 1 |
| Robert Towers | Zayde | Partner | 1 | 1 |
| Heather McPhaul | Security Officer | Rhonda | 1 | 1 |
← Grey's Anatomy × Will & Grace
Cast data from TVmaze, licensed CC BY-SA 4.0.