All 154 actors in both Murder, She Wrote and St. Elsewhere
154 actors have appeared in both Murder, She Wrote and St. Elsewhere, across 401 episodes. The most-credited is William Windom, Dr. Seth Hazlitt, Sam Breen in Murder, She Wrote and Charlie Halloran in St. Elsewhere.
| Actor | In Murder, She Wrote | In St. Elsewhere | Eps | Eps |
|---|---|---|---|---|
| William Windom | Dr. Seth Hazlitt, Sam Breen | Charlie Halloran | 48 | 1 |
| Bonnie Bartlett | Marilyn North | Ellen Craig | 1 | 36 |
| Barbara Whinnery | Gretchen Pashko | Dr. Cathy Martin | 1 | 32 |
| Herb Edelman | NYPD Lieutenant Artie Gelber, George, Lieutenant Varick | Richard Clarendon | 9 | 18 |
| Ellen Bry | Linda Stevens | Nurse Shirley Daniels | 1 | 20 |
| Norman Lloyd | Edward St. Cloud, Lloyd Marcus, Philip Arkham | Dr. Daniel Auschlander | 3 | 17 |
| Kim Miyori | Gayle Yamada | Dr. Wendy Armstrong | 1 | 17 |
| Paul Sand | Horace Lynchfield | Dr. Michael Ridley | 1 | 12 |
| Marian Mercer | Penelope Hope Daniels | Eve Leighton | 1 | 8 |
| Bruce Gray | Ted Hartley, Dean Merrill, R. L. Pierson | Colonel Harvey Blackwell | 5 | 1 |
| John Schuck | Captain Davis, Chief Merton P. Drock | Andrew Wegener | 2 | 4 |
| Melody Anderson | Katherine Aaron | Nurse Jill Roberts | 1 | 5 |
| Stephen Furst | Sgt. Paulson | Dr. Elliot Axelrod | 1 | 5 |
| Conrad Janis | Dr. Yambert, Jason O'Connell, Miles Hatcher | Prosecuting Attorney | 3 | 2 |
| Stephen Elliott | Dr. Samuel "Sam" Garver | Manny Schecter | 1 | 8 |
| Alan Oppenheimer | Dr. Raymond Auerbach | Ira Rosenthal | 2 | 2 |
| Barney Martin | Lt. Timothy Hanratty | Mr. Duffy | 2 | 2 |
| Kate Mulgrew | Joanna Rollins, Sonny Greer | Helen O'Casey | 2 | 2 |
| Melinda Culea | Nicole Gary, Sara Lloyd | McPhail | 2 | 1 |
| Ben Slack | Burnsie, Frank Christy | Louie, Mr. Samrock | 2 | 2 |
| Brian McNamara | Harry Neville, Randall Sloan, Tom McCray | Michael Endicott | 3 | 3 |
| France Nuyen | Emma Soon Dunbar | Dr. Paulette Kiem | 1 | 3 |
| Jack Bannon | Chief Inspector Bernicker, Dr. Mark Brady | Stephen MacAllister | 2 | 4 |
| Jamie Rose | Anne Lowery, Lisa McCauley | Dr. Susan Birch | 2 | 4 |
| Piper Laurie | Peggy Shannon | Fran Singleton | 1 | 3 |
| Ray Girardin | Lt. Casey, George Tibbits | TBD | 3 | 1 |
| Robert Hogan | Dr. Wylie Graham, FBI Agent Guilfoyle, Lt. Bergkamp | Mr. Greely | 4 | 1 |
| David Ackroyd | Bert Lown, Nate Parsons, Prosecutor Tom Casselli | Colonel Chuck Cochrane | 3 | 3 |
| Deborah White | Matty Marsh | Nina Morrison | 1 | 5 |
| Doris Roberts | Helen Owens, Mrs. Leah Colfax | Cora | 2 | 1 |
| Michael Learned | Maria Hudson | Sister Domenica | 1 | 2 |
| Al Ruscio | Santo Angelini | Raleigh, Mr. Morlin | 1 | 3 |
| Brenda Vaccaro | Didi Blair, Mimi Harcourt, Sheila Kowalski Finley | Rose Orso | 3 | 1 |
| David Wayne | Cyrus Leffingwell | Dr. George Wyler | 1 | 3 |
| Alan Fudge | Brian Wade, Councilman Axelrod, Derek St. James | TBD | 4 | 1 |
| James Sutorius | Lawrence Coyle, Mark Tower, Professor Ron Mercer | Sam Hendrix | 4 | 2 |
| Bill Macy | Myron Kinkaid, Uncle Ben Mayberry | Hershel Millstein | 2 | 2 |
| Corinne Bohrer | Bea Huffington, Helena McKenna | Suzanne McConnell | 2 | 1 |
| Edith Diaz | Emma | Morena | 1 | 3 |
| James Stephens | Police Det. Lt. Bert Donovan, U.S. Treasury Agent Lennihan | Young Dr. Daniel Auschlander | 2 | 1 |
| Joey Aresco | Rocco Pastolino | Bruce | 1 | 1 |
| Marilyn Jones | Bridie Harmon, Linda Dixon, Marie Comouche | Allyson Gladden O'Casey | 3 | 1 |
| Michael Brandon | Alex Weaver | Anthony Gifford | 1 | 1 |
| Scott Paulin | Dr. Marshall | Stephen Craig | 1 | 4 |
| Tom Henschel | Dr. Framer, Terence Gideon | Maintenance Man Kyle | 2 | 4 |
| Roxanne Reese | Nancy Murray | Nurse Louise Safford | 1 | 5 |
| Christopher Allport | Donald Granger, Jim Harlan | Mr. Kent | 2 | 2 |
| Robert Costanzo | Det. Lt. Greco, Freddie | Mr. Broadwater | 2 | 2 |
| Alex Rocco | Bert Yardley, Ernie Santini | Roger | 2 | 1 |
| Austin Pendleton | Barney Gunderson | Mr. Entertainment | 1 | 2 |
| Brian Kerwin | Andy Townsend | Terence O'Casey | 1 | 2 |
| Ramon Bieri | Captain Frank Browning, Nick Zavakis, Pat Phillips | Gene Galecki | 3 | 3 |
| Stephen Shortridge | Steve Gamble | TBD | 1 | 2 |
| Conchata Ferrell | Harriet Lundgren | Gina Barnett | 1 | 1 |
| Louis Giambalvo | Lt. Blaisdell | Anthony Rizzo | 1 | 1 |
| Paul Lieber | Milt Solomon | Arrested Suspect | 1 | 1 |
| Sandy McPeak | Bill Spenser, Morgan Rogers, Spruce Osborne | Mr. Reinhardt | 3 | 1 |
| Dody Goodman | Beverly Hills | Gretchen Parks | 1 | 2 |
| Richard Gilliland | Charles Weatherly, Steve Landon | Mr. Fitzsimmons | 2 | 1 |
| David Elliott | Paramedic, Young Officer | Kevin O'Connor | 2 | 2 |
| Harry Stephens | Doctor, Ned | Joe Roecklin, Technician | 2 | 2 |
| Linda Kelsey | Diana Simms, Ellen Levering, Mary Stamm | Cape Resident | 3 | 1 |
| Sandy Ward | Barnes, Henry Riddett, Norman Trent | Russell | 3 | 1 |
| Beah Richards | Emma Coop, Ola Mae | Regina | 2 | 1 |
| Diana Canova | Joan Germaine, Mary Margaret 'Maggie' McCauley | Dr. Valerie Harding | 2 | 1 |
| Dick O'Neill | Benny Tibbles | Mr. O'Connor | 1 | 2 |
| Fran Bennett | Detective MacKenzie | Nurse Julie Attucks | 1 | 1 |
| Heather McAdam | Jane Ballinger | Sandy Malin | 1 | 1 |
| Jo de Winter | Deborah Tarkington | Iris York, TBD | 1 | 2 |
| Jonathan Goldsmith | Mitch Randall | Dr. Julius Markes | 1 | 2 |
| Macon McCalman | Hotel Detective Fritz Rice, Nolan Hayes | Henry Judson | 2 | 1 |
| Nicholas Pryor | Harry Parmel, Theo Coyle | Prison Doctor | 2 | 1 |
| Pat Hingle | Ret. Det. Barney Kale, Zach Franklin | Walter Schaeffer | 2 | 1 |
| Sam Anderson | Ethan Stevens | Mr. McGrath | 1 | 1 |
| Wendy Phillips | Nancy Dalton | Diane Hassett | 1 | 1 |
| Milos Kirek | Dukhov | Mr. Podgorny | 1 | 2 |
| Howard Witt | Bart Nelson | TBD | 1 | 1 |
| James Coco | Horatio Baldwin | Arnie | 1 | 1 |
| Alan Feinstein | George Woodward, Mike Freelander | Michael Stewart | 2 | 1 |
| David Knell | Acting Police Chief Wylie Ledbetter | Matthew Brody | 1 | 1 |
| Howard McGillin | Charles Lockner | Scott | 1 | 1 |
| Jackie Cooper | Carl Schulman / Neil Fletcher | Young Dr. David Domedion | 2 | 1 |
| James McEachin | Grover Dillon | Harris Jeffries | 1 | 1 |
| Julius Harris | Jack Lee Johnson | Earl | 1 | 1 |
| Robert Gray | Albert Cromwell | Dr. Benzig | 1 | 1 |
| Tom Byrd | Paul Gambini | Kevin Hooper | 1 | 1 |
| Albert Salmi | Joe Downing | Leo Rushcom | 1 | 1 |
| Anne Gee Byrd | Widow | Mrs. Brennan | 1 | 1 |
| Cotter Smith | Robert Rhine | Dr. Rowe | 1 | 1 |
| Ed Lauter | Sheriff Orville Yates | Stan Morgen | 1 | 1 |
| John Dennis Johnston | Peter Fargo | Nick Moats | 1 | 1 |
| Joseph Ruskin | Ivanov | Dr. Jonas Wisner | 1 | 1 |
| Lurene Tuttle | Agnes Cochran | Ellen's Mother | 1 | 1 |
| Millie Slavin | Celia Terhune | Maggie | 1 | 1 |
| Norman Burton | Drew Narramore | Monsignor | 1 | 1 |
| Pat Corley | Frank Kelso | Norman Wyler | 1 | 1 |
| Paul Carafotes | Ramon | TBD | 1 | 1 |
| Virginia Capers | Margo Webster | Admit Clerk | 1 | 1 |
| Peter Van Norden | CIA Agent Dennis Quinlan | Bill Fulkerson, Patient | 1 | 2 |
| Alex Henteloff | Raymond Parnell | Dr. Cosco | 1 | 1 |
| Earl Boen | Sgt. Howard Sternhagen | Walter Lankau | 1 | 1 |
| Howard Duff | Ralph / Stephen Earl | Herbie | 1 | 1 |
| Liz Sheridan | Rose Tessler | Dr. Susan Mauri | 1 | 1 |
| Ralph M. Clift | Clerk, Wedding Guest | Maurice | 2 | 1 |
| Tony Bill | Mark Lee Reynolds | Brian Whitehill | 1 | 1 |
| Valerie Wildman | Diane Weaver | Woman in Bar | 1 | 1 |
| John C. Becher | Optometrist, Station Master | Dr. Mott | 2 | 1 |
| Dallas Cole | Nerissa | Amazon Priestess | 1 | 1 |
| Kathleen Lloyd | Paula Roman | Lorraine | 1 | 1 |
| Penny Santon | Mrs. Rizzo | Frannie Catalano | 1 | 1 |
| Hartley Silver | Hypnotized Person #2, Man | Man in Chapel | 2 | 1 |
| Richard Jamison | Delivery Man | Cop, Security Guard | 1 | 2 |
| Alma Beltran | Rosa | Nurse Vela | 1 | 1 |
| Claire Malis | Emily Bryce | Mrs. Stewart | 1 | 1 |
| David Sage | Stavros | Surgeon | 1 | 1 |
| Douglas Rowe | Proprietor | Dr. Anspaugh | 1 | 1 |
| Gillian Eaton | Landlady | Dr. Fanning | 1 | 1 |
| Henry G. Sanders | Skycap | Guard Neil Baldwin | 1 | 1 |
| Reuven Bar-Yotam | Chef Robert | Nikos Papandrao | 1 | 1 |
| Tom Tarpey | Doctor | Mr. Kotlarz | 1 | 1 |
| Arnold F. Turner | Security Guard | Policeman | 1 | 1 |
| Barbara Perry | Party Guest | Dietician | 1 | 1 |
| Beau Starr | Policeman on Boat | Chuck DeMita | 1 | 1 |
| John Furlong | John Winslow Wilson | Sea Captain | 1 | 1 |
| Kate Randolph Burns | Madge | Sandra Eff | 1 | 1 |
| Kres Mersky | Policewoman | Marie Camden | 1 | 1 |
| Robert Jayne | Eric Marsh | Stan Morgen, Jr. | 1 | 1 |
| Yolanda Lloyd Delgado | Caterer | Mrs. Imperi | 1 | 1 |
| Chris Hebert | Tommy Rutledge | Billy McDermott | 1 | 1 |
| John C. Mooney | Doctor | Patrolman | 1 | 1 |
| Judy Jean Berns | Fundraiser Organizer | Mrs. Kotlarz | 1 | 1 |
| Kerry Noonan | Student #2 | Mother | 1 | 1 |
| Louise Fitch | Nosy Neighbor | Admissions Volunteer | 1 | 1 |
| Milt Oberman | Vet | Photographer | 1 | 1 |
| Robert Rothwell | Lucas McCoy | Jury Foreman | 1 | 1 |
| Sue Bugden | Wife | Nurse | 1 | 1 |
| Viola Kates Stimpson | Elderly Lady | Mrs. Konover | 1 | 1 |
| B.J. Ward | Chairwoman | Mrs. Elway | 1 | 1 |
| Bob Lee | Ad-Lib Man | Man on Airplane | 1 | 1 |
| Charles Sweigart | Uniformed Officer | Guardsman | 1 | 1 |
| Eda Reiss Merin | Dorothy Fremont | Mrs. Gustas | 1 | 1 |
| Nick Savage | Leather Guy | Speedball | 1 | 1 |
| Robert Beecher | Elias Cobb | Mr. Stratos | 1 | 1 |
| Robert Hackman | Policeman #1 | Plumber | 1 | 1 |
| Conrad Bachmann | Mills Satberry (Office Manager) | Gentleman | 1 | 1 |
| Ed Hooks | Bellman | Mr. Gaudet | 1 | 1 |
| Fredric Cook | Aaronson | Greek Orthodox Priest | 1 | 1 |
| Harold Ayer | Sexton | Minister | 1 | 1 |
| John Christy Ewing | Dr. Benson | TBD | 1 | 1 |
| Timothy Jecko | Townsperson #3 | Speaker | 1 | 1 |
| Howard George | Desk Sergeant | Detective Enright | 1 | 1 |
| Dan Chambers | Cab Driver | Ken Meyer | 1 | 1 |
| Erik Holland | Detective Mack Brody | Dr. Sven Holstrum | 1 | 1 |
| Rob Monroe | Alex | Panhandler | 1 | 1 |
← Murder, She Wrote × St. Elsewhere
Cast data from TVmaze, licensed CC BY-SA 4.0.