All 68 actors in both Supergirl and The 100
68 actors have appeared in both Supergirl and The 100, across 226 episodes. The most-credited is Sachin Sahel, McGill in Supergirl and Eric Jackson in The 100.
| Actor | In Supergirl | In The 100 | Eps | Eps |
|---|---|---|---|---|
| Sachin Sahel | McGill | Eric Jackson | 2 | 59 |
| Luisa d'Oliveira | Breathtaker | Emori | 2 | 44 |
| Brenda Strong | Lillian Luthor | Queen Nia | 23 | 3 |
| Dichen Lachman | Roulette / Victoria Sinclair | Anya | 2 | 7 |
| Izabela Vidovic | Young Kara Zor-El, J'onzz's Daughter | Charlotte | 5 | 2 |
| Chris Browning | Ben Krull / Reactron | Jake Griffin | 1 | 4 |
| Paul Lazenby | Mandrax, Lead Fireman | Rockline Warrior, Sidekick | 3 | 4 |
| Bethany Brown | Instructor | Jade | 1 | 10 |
| JoJo Ahenkorah | DEO Agent #1 | Costa | 1 | 10 |
| Glenn Ennis | Draaga, Eye-Patched Alien | Ryder, Machete | 2 | 4 |
| Crystal Balint | Secretary Brown | Gemma Cadogan | 3 | 1 |
| Ben Sullivan | Guard | Riley | 2 | 6 |
| Lisa Chandler | Bystander #2, Soccer Mom | Observant Guard | 2 | 1 |
| Sean Kuling | DEO Agent One | Cassius | 2 | 7 |
| James Michalopolous | Goon 1, Igor Starros | Fio | 2 | 4 |
| Marshall Bingham | Guard #2, Robber | Miranda's Royal Guard | 3 | 1 |
| Nick Hunnings | Kopy | Lee | 1 | 4 |
| Brea Schneider | Caroline O'Conner | COG Warrior | 1 | 1 |
| Jennifer Cheon | Midnight | Dakiva | 1 | 1 |
| Malcolm Masters | Dr. Niles Jarrod | Conductor Corbett | 2 | 2 |
| Michael Adamthwaite | Cooper | Reaper | 2 | 1 |
| Michael Rogers | Hannibal | Denby | 1 | 2 |
| Nesta Cooper | Tanya | Shay | 2 | 1 |
| Ryan Hesp | Agent Sloan | Man | 2 | 1 |
| Victor Zinck Jr. | Barrage / Phillip Karnowsky | Dax | 1 | 2 |
| Georgia Hacche | Woman | Denae | 1 | 3 |
| Reese Alexander | Warden | Guard | 2 | 2 |
| Bob Frazer | Luke's Father, Roger Hayden / Psycho Pirate | Captain Stevens | 2 | 1 |
| David Lennon | Cop | Tarik | 1 | 3 |
| Emily Haine | Woman | Keenan Mykulak | 1 | 3 |
| Sarwan Badesha | Onlooker | Arker | 1 | 1 |
| Hamza Fouad | Agent Lawrence | Terrorist Abductor | 1 | 2 |
| Jason Vaisvila | Boris | Ice Nation Healer | 2 | 1 |
| Jay Clift | Lead FBI Agent | Shield Guard Patrol #2 | 1 | 1 |
| John DeSantis | Draaga | Gideon | 1 | 2 |
| Mark Gibbon | General Zod | Grounder #1 / Bounty Hunter | 1 | 2 |
| Kaylah Zander | Mother | Tosh | 1 | 2 |
| Serge Jaswal | Navigator | Brixton Guard | 2 | 1 |
| Hugo Raymundo | Guard, Guard #1 | Hugo | 2 | 1 |
| Mik Byskov | Mr. Samuel Bernard | Otan | 1 | 2 |
| Chad Riley | Prison Guard | Osias | 1 | 1 |
| Christina Lewall | Trauma Doctor | Armed Guard | 1 | 1 |
| Fulvio Cecere | Massimo | Inspector Grus | 1 | 1 |
| Ian Butcher | Lionel Luthor | Bryson | 1 | 3 |
| Jason Cermak | Caldwell | Hull | 1 | 1 |
| Tricia Collins | Reporter #2 | Tory | 1 | 1 |
| Jaeson Lee | DEO Agent #1, Police Officer #2 | Tomac | 2 | 1 |
| Adam Ballantyne | Child of Liberty #1, Second Looter | Dying Grounder | 2 | 1 |
| Alison Thornton | Young Girl | Tris | 1 | 1 |
| Corey Schmitt | Suspect | Prisoner #2 | 1 | 1 |
| Jennifer Koenig | Dark Kryptonian #1 | Wailing Woman | 1 | 1 |
| Patrick Sabongui | Captain David Singh | Sindri | 1 | 2 |
| Shayn Walker | Police Officer | Trikru Warrior | 1 | 1 |
| Tori Katongo | Supreme #2 | Arker Woman | 1 | 1 |
| Jason Bell | Cadmus Guard, COL 1 | Scar | 2 | 1 |
| Emy Aneke | Shiv | Mt. Weather Soldier #1 | 1 | 1 |
| Mark Krysko | Head Guard | Azgeda Speaking Warrior | 1 | 1 |
| Theresa Wong | ER Doctor | Eriko's Mom | 1 | 1 |
| Jay Hindle | Joe Ford | Supervising Med Tech | 1 | 1 |
| Michael Jonsson | Klaus | Esop | 1 | 1 |
| Donald Sales | Platoon Captain | Man | 1 | 1 |
| Jason Beaudoin | Dmitry | Rafel | 1 | 1 |
| Marcello Guedes | Young Malefic | Sean | 1 | 1 |
| Dean Redman | Shuster | Guard | 1 | 1 |
| Phillip Mitchell | Drug Buyer | Large Prisoner | 1 | 1 |
| Jesse Stretch | Bold Inmate | Huge Wonkru Man | 1 | 1 |
| C. Douglas Quan | Mr. Lloyd Li | Eriko's Dad | 1 | 1 |
| Jason Bempong | Moe | Beautiful Young Man | 1 | 1 |
Cast data from TVmaze, licensed CC BY-SA 4.0.